Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst
The levels of dopamine (DA) in living organisms have strong effects on many biological processes and diseases, such as Parkinson's disease and Alzheimer's disease. Therefore, it has great significance for sensitive and selective detection of DA. Herein, the AuPd@Fe2O3 nanoparticles-based e...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Advanced Sensor and Energy Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773045X23000031 |
| _version_ | 1811159907475390464 |
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| author | Mengjiao Dai Qunyan Zhu Dongxue Han Li Niu Zhenxin Wang |
| author_facet | Mengjiao Dai Qunyan Zhu Dongxue Han Li Niu Zhenxin Wang |
| author_sort | Mengjiao Dai |
| collection | DOAJ |
| description | The levels of dopamine (DA) in living organisms have strong effects on many biological processes and diseases, such as Parkinson's disease and Alzheimer's disease. Therefore, it has great significance for sensitive and selective detection of DA. Herein, the AuPd@Fe2O3 nanoparticles-based electrochemical (EC) sensor (AuPd@Fe2O3 NPs/GCE) is developed for chronoamperometric detection of DA with high sensitivity and good anti-interference ability through simple immobilization of AuPd@Fe2O3 nanoparticles on glassy carbon electrode (GCE) by Nafion. Under the application of oxidation potential, the AuPd@Fe2O3 NPs/GCE exhibits good electrocatalytic activity toward DA, which enables to linearly detect DA in the range of 10 nM–831.61 μM (R2 = 0.9983). The AuPd@Fe2O3 NPs/GCE also shows good selectivity and reproducibility for the detection of DA. Furthermore, the practicability of AuPd@Fe2O3 NPs/GCE has been demonstrated by detection of DA in dopamine hydrochloride injection and human serum. |
| first_indexed | 2024-04-10T05:48:37Z |
| format | Article |
| id | doaj.art-64cbaf01b23e4b7ab1ee2dc0bde74a10 |
| institution | Directory Open Access Journal |
| issn | 2773-045X |
| language | English |
| last_indexed | 2024-04-10T05:48:37Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Advanced Sensor and Energy Materials |
| spelling | doaj.art-64cbaf01b23e4b7ab1ee2dc0bde74a102023-03-05T04:26:21ZengElsevierAdvanced Sensor and Energy Materials2773-045X2023-03-0121100048Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalystMengjiao Dai0Qunyan Zhu1Dongxue Han2Li Niu3Zhenxin Wang4State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; University of Science and Technology of China, Hefei 230026, ChinaState Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; Corresponding author.Guangzhou Key Laboratory of Sensing Materials and Devices, Center for Advanced Analytical Science, School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Psychoactive Substances Monitoring and Safety, Anti-Drug Technology Center of Guangdong Province, Guangzhou 510230, ChinaGuangzhou Key Laboratory of Sensing Materials and Devices, Center for Advanced Analytical Science, School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, ChinaState Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; University of Science and Technology of China, Hefei 230026, China; National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, ChinaThe levels of dopamine (DA) in living organisms have strong effects on many biological processes and diseases, such as Parkinson's disease and Alzheimer's disease. Therefore, it has great significance for sensitive and selective detection of DA. Herein, the AuPd@Fe2O3 nanoparticles-based electrochemical (EC) sensor (AuPd@Fe2O3 NPs/GCE) is developed for chronoamperometric detection of DA with high sensitivity and good anti-interference ability through simple immobilization of AuPd@Fe2O3 nanoparticles on glassy carbon electrode (GCE) by Nafion. Under the application of oxidation potential, the AuPd@Fe2O3 NPs/GCE exhibits good electrocatalytic activity toward DA, which enables to linearly detect DA in the range of 10 nM–831.61 μM (R2 = 0.9983). The AuPd@Fe2O3 NPs/GCE also shows good selectivity and reproducibility for the detection of DA. Furthermore, the practicability of AuPd@Fe2O3 NPs/GCE has been demonstrated by detection of DA in dopamine hydrochloride injection and human serum.http://www.sciencedirect.com/science/article/pii/S2773045X23000031Electrochemical sensorAuPd@Fe2O3 nanoparticlesDopamineHigh sensitivityGood anti-interference ability |
| spellingShingle | Mengjiao Dai Qunyan Zhu Dongxue Han Li Niu Zhenxin Wang Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst Advanced Sensor and Energy Materials Electrochemical sensor AuPd@Fe2O3 nanoparticles Dopamine High sensitivity Good anti-interference ability |
| title | Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst |
| title_full | Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst |
| title_fullStr | Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst |
| title_full_unstemmed | Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst |
| title_short | Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe2O3 nanoparticles as catalyst |
| title_sort | sensitive and selective electrochemical sensor for the detection of dopamine by using aupd fe2o3 nanoparticles as catalyst |
| topic | Electrochemical sensor AuPd@Fe2O3 nanoparticles Dopamine High sensitivity Good anti-interference ability |
| url | http://www.sciencedirect.com/science/article/pii/S2773045X23000031 |
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