Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study
Objective(s): Considering the fact that the standardized uptake value (SUV) of a normal lung tissue is expressed as x±SD, x+3×SD could be considered as the threshold value to outline the internal tumor volume (ITV) of a lung neoplasm. Methods: Three hollow models were filled with 55.0 kBq/mL fluorin...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2016-01-01
|
| Series: | Asia Oceania Journal of Nuclear Medicine and Biology |
| Subjects: | |
| Online Access: | http://aojnmb.mums.ac.ir/pdf_5341_cf4356ab0137c4d9d3f42ce169c4e5be.html |
| _version_ | 1828751411284803584 |
|---|---|
| author | yangchun chen Xiangrong Chen Ji-an Liu Fanyong Li |
| author_facet | yangchun chen Xiangrong Chen Ji-an Liu Fanyong Li |
| author_sort | yangchun chen |
| collection | DOAJ |
| description | Objective(s): Considering the fact that the standardized uptake value (SUV) of a normal lung tissue is expressed as x±SD, x+3×SD could be considered as the threshold value to outline the internal tumor volume (ITV) of a lung neoplasm. Methods: Three hollow models were filled with 55.0 kBq/mL fluorine18- fluorodeoxyglucose (18F-FDG) to represent tumors. The models were fixed to a barrel filled with 5.9 kBq/mL 18F-FDG to characterize normal lung tissues as a phantom. The PET/CT images of the phantom were acquired at rest. Then, the barrel was moved periodically to simulate breathing while acquiring PET/CT data. Volume recovery coefficient (VRC) was applied to evaluate the accuracy of ITVs. For statistical analysis, paired t-test and analysis of variance were applied. Results: The VRCs ranged from 0.74 to 0.98 and significantly varied among gross tumor volumes for delineating ITV (P0.05), whereas VRC decreased with increasing distance in three-dimensional PET scans (P |
| first_indexed | 2024-12-10T20:53:05Z |
| format | Article |
| id | doaj.art-64d37816d1ad4c8fb905b6ce141e2512 |
| institution | Directory Open Access Journal |
| issn | 2322-5718 2322-5726 |
| language | English |
| last_indexed | 2024-12-10T20:53:05Z |
| publishDate | 2016-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Asia Oceania Journal of Nuclear Medicine and Biology |
| spelling | doaj.art-64d37816d1ad4c8fb905b6ce141e25122022-12-22T01:34:02ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262016-01-0141384410.7508/aojnmb.2016.04.0065341Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Studyyangchun chen0Xiangrong Chen1Ji-an Liu2Fanyong Li3Department of Nuclear Medicine, Quanzhou First Hospital, Fujian Medical University, Quanzhou, ChinaDepartment of Radiology, Quanzhou First Hospital, Fujian Medical University, Quanzhou, ChinaGuangdong Provincial Key Laboratory of Micro-nano Manufacturing Technology and Equipment, Guangdong University of Technology, Guangzhou, ChinaThe PET-CT Center, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, ChinaObjective(s): Considering the fact that the standardized uptake value (SUV) of a normal lung tissue is expressed as x±SD, x+3×SD could be considered as the threshold value to outline the internal tumor volume (ITV) of a lung neoplasm. Methods: Three hollow models were filled with 55.0 kBq/mL fluorine18- fluorodeoxyglucose (18F-FDG) to represent tumors. The models were fixed to a barrel filled with 5.9 kBq/mL 18F-FDG to characterize normal lung tissues as a phantom. The PET/CT images of the phantom were acquired at rest. Then, the barrel was moved periodically to simulate breathing while acquiring PET/CT data. Volume recovery coefficient (VRC) was applied to evaluate the accuracy of ITVs. For statistical analysis, paired t-test and analysis of variance were applied. Results: The VRCs ranged from 0.74 to 0.98 and significantly varied among gross tumor volumes for delineating ITV (P0.05), whereas VRC decreased with increasing distance in three-dimensional PET scans (Phttp://aojnmb.mums.ac.ir/pdf_5341_cf4356ab0137c4d9d3f42ce169c4e5be.htmlGross tumor volumeinternal tumor volumepositron emission tomographystandardized uptake value |
| spellingShingle | yangchun chen Xiangrong Chen Ji-an Liu Fanyong Li Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study Asia Oceania Journal of Nuclear Medicine and Biology Gross tumor volume internal tumor volume positron emission tomography standardized uptake value |
| title | Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study |
| title_full | Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study |
| title_fullStr | Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study |
| title_full_unstemmed | Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study |
| title_short | Background-Based Delineation of Internal Tumor Volumes on Static Positron Emission Tomography in a Phantom Study |
| title_sort | background based delineation of internal tumor volumes on static positron emission tomography in a phantom study |
| topic | Gross tumor volume internal tumor volume positron emission tomography standardized uptake value |
| url | http://aojnmb.mums.ac.ir/pdf_5341_cf4356ab0137c4d9d3f42ce169c4e5be.html |
| work_keys_str_mv | AT yangchunchen backgroundbaseddelineationofinternaltumorvolumesonstaticpositronemissiontomographyinaphantomstudy AT xiangrongchen backgroundbaseddelineationofinternaltumorvolumesonstaticpositronemissiontomographyinaphantomstudy AT jianliu backgroundbaseddelineationofinternaltumorvolumesonstaticpositronemissiontomographyinaphantomstudy AT fanyongli backgroundbaseddelineationofinternaltumorvolumesonstaticpositronemissiontomographyinaphantomstudy |