Endocrinopathies in thalassemia - a review

Improved treatment has increased survival of patients with thalassemia. However, they still suffer from several endocrine complications mainly as a result of iron overload from multiple transfusions. Endocrinopathies manifest as early as the first decade of life, affecting growth, puberty, psycholog...

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Main Authors: Tahniyah Haq, Shapur Ikhtaire, Farzana Rahman, Nishat Nayla Aurpa
Format: Article
Language:English
Published: Ibrahim Medical College 2021-05-01
Series:IMC Journal of Medical Science
Online Access:https://www.imcjms.com/registration/journal_full_text/375
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author Tahniyah Haq
Shapur Ikhtaire
Farzana Rahman
Nishat Nayla Aurpa
author_facet Tahniyah Haq
Shapur Ikhtaire
Farzana Rahman
Nishat Nayla Aurpa
author_sort Tahniyah Haq
collection DOAJ
description Improved treatment has increased survival of patients with thalassemia. However, they still suffer from several endocrine complications mainly as a result of iron overload from multiple transfusions. Endocrinopathies manifest as early as the first decade of life, affecting growth, puberty, psychological development and quality of life. The presence of concomitant anemia, chronic liver disease and cardiomyopathy affect the development and treatment of endocrine disorders, making endocrinopathies in thalassemia a complex disorder. This review focuses on the pathogenesis, diagnosis and treatment of endocrinopathies in transfusion and non transfusion dependent thalassemia. The main points that should be considered in the management of endocrine disorders in a patient with thalassemia are highlighted in this review. IMC J Med Sci 2021; 15(1): 008. OPEN ACCESS *Correspondence: Tahniyah Haq, Department of Endocrinology, Room 1620, 15th Floor, Block D, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh. Email: tahniyah81@gmail.com
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spelling doaj.art-64dd4f64530a4c2fa2203b45b79bc92c2022-12-21T21:27:29ZengIbrahim Medical CollegeIMC Journal of Medical Science2519-17212519-15862021-05-0115119Endocrinopathies in thalassemia - a reviewTahniyah Haq0Shapur Ikhtaire1Farzana Rahman2Nishat Nayla Aurpa3Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshDepartment of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshDepartment of Hematology, Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshFulbaria Upazilla Health Complex,Fulbaria , Mymensingh, BangladeshImproved treatment has increased survival of patients with thalassemia. However, they still suffer from several endocrine complications mainly as a result of iron overload from multiple transfusions. Endocrinopathies manifest as early as the first decade of life, affecting growth, puberty, psychological development and quality of life. The presence of concomitant anemia, chronic liver disease and cardiomyopathy affect the development and treatment of endocrine disorders, making endocrinopathies in thalassemia a complex disorder. This review focuses on the pathogenesis, diagnosis and treatment of endocrinopathies in transfusion and non transfusion dependent thalassemia. The main points that should be considered in the management of endocrine disorders in a patient with thalassemia are highlighted in this review. IMC J Med Sci 2021; 15(1): 008. OPEN ACCESS *Correspondence: Tahniyah Haq, Department of Endocrinology, Room 1620, 15th Floor, Block D, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh. Email: tahniyah81@gmail.comhttps://www.imcjms.com/registration/journal_full_text/375
spellingShingle Tahniyah Haq
Shapur Ikhtaire
Farzana Rahman
Nishat Nayla Aurpa
Endocrinopathies in thalassemia - a review
IMC Journal of Medical Science
title Endocrinopathies in thalassemia - a review
title_full Endocrinopathies in thalassemia - a review
title_fullStr Endocrinopathies in thalassemia - a review
title_full_unstemmed Endocrinopathies in thalassemia - a review
title_short Endocrinopathies in thalassemia - a review
title_sort endocrinopathies in thalassemia a review
url https://www.imcjms.com/registration/journal_full_text/375
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