Intraocular pressure and influencing systemic health parameters in a Korean population
Aim: To evaluate the relationship between intraocular pressure (IOP) and systemic health parameters such as age, gender, body mass index (BMI), total cholesterol, high density lipoprotein (HDL), and triglyceride (TG) in a Korean population. Materials and Methods: A total of 30,893 healthy subjects u...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=3;spage=305;epage=310;aulast=Han |
| _version_ | 1818217084080881664 |
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| author | Young Sang Han Ji Woong Lee Jong Soo Lee |
| author_facet | Young Sang Han Ji Woong Lee Jong Soo Lee |
| author_sort | Young Sang Han |
| collection | DOAJ |
| description | Aim: To evaluate the relationship between intraocular pressure (IOP) and systemic health parameters such as age, gender, body mass index (BMI), total cholesterol, high density lipoprotein (HDL), and triglyceride (TG) in a Korean population. Materials and Methods: A total of 30,893 healthy subjects underwent automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, and blood samplings for total cholesterol, HDL, and TG. Seven age groups were divided by decades ranging from 20 to 29 years to 80 + years. The association between IOP and BMI, plasma lipid profiles was examined using cross-sectional analysis. Results: The mean age of subjects was 47.7 years. The mean IOP of subjects was 15.4 ± 3.2 mmHg for both eyes. The mean IOP of men was significantly higher than women ( P = 0.000). By multiple linear regression analysis, IOP was positively associated with gender (male), BMI, total cholesterol, and TG and negatively associated with age ( P = 0.000). BMI, total cholesterol, and TG had significantly positive correlations with IOP after adjusting for age, gender, and other variables which can influence the IOP ( P = 0.000). Conclusions: In a Korean population, the mean IOP, total cholesterol, TG, and BMI values of men were higher than women. IOP was found to increase with total cholesterol, TG, BMI, and to decrease with only age regardless of sex. |
| first_indexed | 2024-12-12T07:02:14Z |
| format | Article |
| id | doaj.art-64ddd64b391148bd84815cf515e5fbc7 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-12T07:02:14Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-64ddd64b391148bd84815cf515e5fbc72022-12-22T00:33:50ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892014-01-0162330531010.4103/0301-4738.116453Intraocular pressure and influencing systemic health parameters in a Korean populationYoung Sang HanJi Woong LeeJong Soo LeeAim: To evaluate the relationship between intraocular pressure (IOP) and systemic health parameters such as age, gender, body mass index (BMI), total cholesterol, high density lipoprotein (HDL), and triglyceride (TG) in a Korean population. Materials and Methods: A total of 30,893 healthy subjects underwent automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, and blood samplings for total cholesterol, HDL, and TG. Seven age groups were divided by decades ranging from 20 to 29 years to 80 + years. The association between IOP and BMI, plasma lipid profiles was examined using cross-sectional analysis. Results: The mean age of subjects was 47.7 years. The mean IOP of subjects was 15.4 ± 3.2 mmHg for both eyes. The mean IOP of men was significantly higher than women ( P = 0.000). By multiple linear regression analysis, IOP was positively associated with gender (male), BMI, total cholesterol, and TG and negatively associated with age ( P = 0.000). BMI, total cholesterol, and TG had significantly positive correlations with IOP after adjusting for age, gender, and other variables which can influence the IOP ( P = 0.000). Conclusions: In a Korean population, the mean IOP, total cholesterol, TG, and BMI values of men were higher than women. IOP was found to increase with total cholesterol, TG, BMI, and to decrease with only age regardless of sex.http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=3;spage=305;epage=310;aulast=Han Clinical profileIndian populationoptic neuritis treatment trialoptic neuritis Decompression of the orbitdiplopiaorbitthyroid exophthalmosthyroid ophthalmopathy Limbus incisionsubconjunctival incisionsutureless manual small-incision cataract surgerywound constructionCentral retinal vein occlusionintravitrealbevacizumabintravitrealtriamcinolone acetonidemacular edema Contrast sensitivityfixationmicroperimeternormative dataretinal sensitivity Optical coherence tomographyoptic disc pitretinal detachmentretinoschisis Homocysteineretinal vein occlusionvisual impairment Diabetic macular edemamonocyte chemoattractant protein-1soluble intracellular adhesion molecule-1vascular endothelial growth factorCompressive optic neuropathyhumphrey visual fieldischemic optic neuropathymultifocal visual evoked potentialoptic neuritis Agebody mass indexgenderhigh density lipoproteinintraocular pressurelipid profilestotal cholesteroltriglyceride |
| spellingShingle | Young Sang Han Ji Woong Lee Jong Soo Lee Intraocular pressure and influencing systemic health parameters in a Korean population Indian Journal of Ophthalmology Clinical profile Indian population optic neuritis treatment trial optic neuritis Decompression of the orbit diplopia orbit thyroid exophthalmos thyroid ophthalmopathy Limbus incision subconjunctival incision sutureless manual small-incision cataract surgery wound construction Central retinal vein occlusion intravitrealbevacizumab intravitrealtriamcinolone acetonide macular edema Contrast sensitivity fixation microperimeter normative data retinal sensitivity Optical coherence tomography optic disc pit retinal detachment retinoschisis Homocysteine retinal vein occlusion visual impairment Diabetic macular edema monocyte chemoattractant protein-1 soluble intracellular adhesion molecule-1 vascular endothelial growth factor Compressive optic neuropathy humphrey visual field ischemic optic neuropathy multifocal visual evoked potential optic neuritis Age body mass index gender high density lipoprotein intraocular pressure lipid profiles total cholesterol triglyceride |
| title | Intraocular pressure and influencing systemic health parameters in a Korean population |
| title_full | Intraocular pressure and influencing systemic health parameters in a Korean population |
| title_fullStr | Intraocular pressure and influencing systemic health parameters in a Korean population |
| title_full_unstemmed | Intraocular pressure and influencing systemic health parameters in a Korean population |
| title_short | Intraocular pressure and influencing systemic health parameters in a Korean population |
| title_sort | intraocular pressure and influencing systemic health parameters in a korean population |
| topic | Clinical profile Indian population optic neuritis treatment trial optic neuritis Decompression of the orbit diplopia orbit thyroid exophthalmos thyroid ophthalmopathy Limbus incision subconjunctival incision sutureless manual small-incision cataract surgery wound construction Central retinal vein occlusion intravitrealbevacizumab intravitrealtriamcinolone acetonide macular edema Contrast sensitivity fixation microperimeter normative data retinal sensitivity Optical coherence tomography optic disc pit retinal detachment retinoschisis Homocysteine retinal vein occlusion visual impairment Diabetic macular edema monocyte chemoattractant protein-1 soluble intracellular adhesion molecule-1 vascular endothelial growth factor Compressive optic neuropathy humphrey visual field ischemic optic neuropathy multifocal visual evoked potential optic neuritis Age body mass index gender high density lipoprotein intraocular pressure lipid profiles total cholesterol triglyceride |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=3;spage=305;epage=310;aulast=Han |
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