Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue
Ifosfamide, an alkylating agent used in cancer treatments, can cause neurotoxicity. The clinical presentation can range from mild symptoms such as acute confusion to non-convulsive seizures, severe irreversible coma, and death. The benefit of methylene blue use in treating ifosfamide-induced metabol...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-07-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/2324709618786769 |
| _version_ | 1818279088413999104 |
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| author | Anusha Vakiti MD Ravi Pilla MD Muhamad Alhaj Moustafa MD Jacinth J. Joseph MD Aarthi G. Shenoy MD |
| author_facet | Anusha Vakiti MD Ravi Pilla MD Muhamad Alhaj Moustafa MD Jacinth J. Joseph MD Aarthi G. Shenoy MD |
| author_sort | Anusha Vakiti MD |
| collection | DOAJ |
| description | Ifosfamide, an alkylating agent used in cancer treatments, can cause neurotoxicity. The clinical presentation can range from mild symptoms such as acute confusion to non-convulsive seizures, severe irreversible coma, and death. The benefit of methylene blue use in treating ifosfamide-induced metabolic encephalopathy is not well established. In this article, we present 2 cases of ifosfamide-induced metabolic encephalopathy responsive to methylene blue treatment. |
| first_indexed | 2024-12-12T23:27:46Z |
| format | Article |
| id | doaj.art-64e47f7b58d74ce0b88036cf5f843b7f |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-12-12T23:27:46Z |
| publishDate | 2018-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-64e47f7b58d74ce0b88036cf5f843b7f2022-12-22T00:07:57ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962018-07-01610.1177/2324709618786769Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene BlueAnusha Vakiti MD0Ravi Pilla MD1Muhamad Alhaj Moustafa MD2Jacinth J. Joseph MD3Aarthi G. Shenoy MD4MedStar Washington Hospital Center, Washington, DC, USAMedStar Washington Hospital Center, Washington, DC, USAMedStar Washington Hospital Center, Washington, DC, USAMedStar Washington Hospital Center, Washington, DC, USAMedStar Washington Hospital Center, Washington, DC, USAIfosfamide, an alkylating agent used in cancer treatments, can cause neurotoxicity. The clinical presentation can range from mild symptoms such as acute confusion to non-convulsive seizures, severe irreversible coma, and death. The benefit of methylene blue use in treating ifosfamide-induced metabolic encephalopathy is not well established. In this article, we present 2 cases of ifosfamide-induced metabolic encephalopathy responsive to methylene blue treatment.https://doi.org/10.1177/2324709618786769 |
| spellingShingle | Anusha Vakiti MD Ravi Pilla MD Muhamad Alhaj Moustafa MD Jacinth J. Joseph MD Aarthi G. Shenoy MD Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue Journal of Investigative Medicine High Impact Case Reports |
| title | Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue |
| title_full | Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue |
| title_fullStr | Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue |
| title_full_unstemmed | Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue |
| title_short | Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue |
| title_sort | ifosfamide induced metabolic encephalopathy in 2 patients with cutaneous t cell lymphoma successfully treated with methylene blue |
| url | https://doi.org/10.1177/2324709618786769 |
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