The Kallikrein-Kinin-System in Experimental Chagas Disease: A Paradigm to Investigate the Impact of Inflammatory Edema on GPCR-mediated pathways of Host Cell Invasion by Trypanosoma cruzi
Chronic chagasic myocarditis (CCM) depends on Trypanosoma cruzi persistence in the myocardium. Studies of the proteolytic mechanisms governing host/parasite balance in peripheral sites of T. cruzi infection revealed that tissue culture trypomastigotes (TCTs) elicit inflammatory edema and stimulate p...
Main Authors: | Julio eScharfstein, Daniele eAndrade, Erik eSvensjö, Ana Carolina eOliveira, Clarissa Rodrigues Nascimento |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-01-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00396/full |
Similar Items
-
Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy
by: Ana Carolina Oliveira, et al.
Published: (2023-04-01) -
Mast Cell Coupling to the Kallikrein–Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease
by: Clarissa R. Nascimento, et al.
Published: (2017-08-01) -
Drugs of the Kallikrein–Kinin System: An Overview
by: François Marceau
Published: (2023-07-01) -
Endothelin-1 receptors play a minor role in the protection against acute Trypanosoma cruzi infection in mice
by: E. Roffê, et al.
Published: (2007-03-01) -
The relationship between clinical phenotype and kallikrein-kinin bioregulation in different forms of arthritis
by: Dino B. A. Tan, et al.
Published: (2023-05-01)