Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines

<p>Abstract</p> <p>Background</p> <p>Metastatic melanoma is a highly chemotherapy resistant tumour. The use of newer targeted therapies alone and in combination with chemotherapy may offer new hope of improving response to treatment. Dasatinib, a multi-target kinase inh...

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Bibliographic Details
Main Authors: Clynes Martin, Crown John, Eustace Alex J, O'Donovan Norma
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/53