Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

ABSTRACT Toxoplasma gondii is a widespread intracellular pathogen infecting humans and a variety of animals. Previous studies have shown that Toxoplasma uses glucose and glutamine as the main carbon sources to support asexual reproduction, but neither nutrient is essential. Such metabolic flexibilit...

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Bibliographische Detailangaben
Hauptverfasser: Ningbo Xia, Shu Ye, Xiaohan Liang, Pu Chen, Yanqin Zhou, Rui Fang, Junlong Zhao, Nishith Gupta, Shuzhen Yang, Jing Yuan, Bang Shen
Format: Artikel
Sprache:English
Veröffentlicht: American Society for Microbiology 2019-06-01
Schriftenreihe:mBio
Schlagworte:
Toxoplasma
apicoplast
lactate
metabolic flexibility
pyruvate kinase
Online Zugang:https://journals.asm.org/doi/10.1128/mBio.00898-19

Online

https://journals.asm.org/doi/10.1128/mBio.00898-19

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