Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in <named-content content-type="genus-species">Toxoplasma gondii</named-content>

ABSTRACT Toxoplasma gondii is a widespread intracellular pathogen infecting humans and a variety of animals. Previous studies have shown that Toxoplasma uses glucose and glutamine as the main carbon sources to support asexual reproduction, but neither nutrient is essential. Such metabolic flexibilit...

Полное описание

Библиографические подробности
Главные авторы: Ningbo Xia, Shu Ye, Xiaohan Liang, Pu Chen, Yanqin Zhou, Rui Fang, Junlong Zhao, Nishith Gupta, Shuzhen Yang, Jing Yuan, Bang Shen
Формат: Статья
Язык:English
Опубликовано: American Society for Microbiology 2019-06-01
Серии:mBio
Предметы:
Toxoplasma
apicoplast
lactate
metabolic flexibility
pyruvate kinase
Online-ссылка:https://journals.asm.org/doi/10.1128/mBio.00898-19

Internet

https://journals.asm.org/doi/10.1128/mBio.00898-19

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