Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the...
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Format: | Article |
Language: | English |
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Tehran University of Medical Sciences
2013-03-01
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Series: | International Journal of Hematology-Oncology and Stem Cell Research |
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Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/462 |
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author | K Goudarzipour M Kajiyazdi A Mahdaviyani |
author_facet | K Goudarzipour M Kajiyazdi A Mahdaviyani |
author_sort | K Goudarzipour |
collection | DOAJ |
description | Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the case of a 10-year-old girl with neurological complications caused by EBV-induced HLH. The patient received rituximab, leading to weakening inflammation associated with EBV infection and suppression of disease through quick treatment. |
first_indexed | 2024-03-12T09:02:37Z |
format | Article |
id | doaj.art-64f6c5be449d4b66a4751adf9be72382 |
institution | Directory Open Access Journal |
issn | 2008-2207 |
language | English |
last_indexed | 2024-03-12T09:02:37Z |
publishDate | 2013-03-01 |
publisher | Tehran University of Medical Sciences |
record_format | Article |
series | International Journal of Hematology-Oncology and Stem Cell Research |
spelling | doaj.art-64f6c5be449d4b66a4751adf9be723822023-09-02T15:34:00ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072013-03-0171Epstein-Barr Virus-Induced Hemophagocytic LymphohistiocytosisK Goudarzipour0M Kajiyazdi1A Mahdaviyani2Mofid, Children's Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.Mofid, Children's Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.Masih Daneshvari Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the case of a 10-year-old girl with neurological complications caused by EBV-induced HLH. The patient received rituximab, leading to weakening inflammation associated with EBV infection and suppression of disease through quick treatment.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/462Epstein - Barr virusEtanerceptHemophagocytic lymphohistiocytosisInfectious mononucleosisSystemic inflammatory response syndromeX-Linked lymphoproliferative disease |
spellingShingle | K Goudarzipour M Kajiyazdi A Mahdaviyani Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis International Journal of Hematology-Oncology and Stem Cell Research Epstein - Barr virus Etanercept Hemophagocytic lymphohistiocytosis Infectious mononucleosis Systemic inflammatory response syndrome X-Linked lymphoproliferative disease |
title | Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis |
title_full | Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis |
title_fullStr | Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis |
title_full_unstemmed | Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis |
title_short | Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis |
title_sort | epstein barr virus induced hemophagocytic lymphohistiocytosis |
topic | Epstein - Barr virus Etanercept Hemophagocytic lymphohistiocytosis Infectious mononucleosis Systemic inflammatory response syndrome X-Linked lymphoproliferative disease |
url | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/462 |
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