Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the...

Full description

Bibliographic Details
Main Authors: K Goudarzipour, M Kajiyazdi, A Mahdaviyani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2013-03-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/462
_version_ 1797719285072658432
author K Goudarzipour
M Kajiyazdi
A Mahdaviyani
author_facet K Goudarzipour
M Kajiyazdi
A Mahdaviyani
author_sort K Goudarzipour
collection DOAJ
description Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the case of a 10-year-old girl with neurological complications caused by EBV-induced HLH. The patient received rituximab, leading to weakening inflammation associated with EBV infection and suppression of disease through quick treatment.
first_indexed 2024-03-12T09:02:37Z
format Article
id doaj.art-64f6c5be449d4b66a4751adf9be72382
institution Directory Open Access Journal
issn 2008-2207
language English
last_indexed 2024-03-12T09:02:37Z
publishDate 2013-03-01
publisher Tehran University of Medical Sciences
record_format Article
series International Journal of Hematology-Oncology and Stem Cell Research
spelling doaj.art-64f6c5be449d4b66a4751adf9be723822023-09-02T15:34:00ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072013-03-0171Epstein-Barr Virus-Induced Hemophagocytic LymphohistiocytosisK Goudarzipour0M Kajiyazdi1A Mahdaviyani2Mofid, Children's Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.Mofid, Children's Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.Masih Daneshvari Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the case of a 10-year-old girl with neurological complications caused by EBV-induced HLH. The patient received rituximab, leading to weakening inflammation associated with EBV infection and suppression of disease through quick treatment.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/462Epstein - Barr virusEtanerceptHemophagocytic lymphohistiocytosisInfectious mononucleosisSystemic inflammatory response syndromeX-Linked lymphoproliferative disease
spellingShingle K Goudarzipour
M Kajiyazdi
A Mahdaviyani
Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
International Journal of Hematology-Oncology and Stem Cell Research
Epstein - Barr virus
Etanercept
Hemophagocytic lymphohistiocytosis
Infectious mononucleosis
Systemic inflammatory response syndrome
X-Linked lymphoproliferative disease
title Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
title_full Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
title_fullStr Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
title_full_unstemmed Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
title_short Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis
title_sort epstein barr virus induced hemophagocytic lymphohistiocytosis
topic Epstein - Barr virus
Etanercept
Hemophagocytic lymphohistiocytosis
Infectious mononucleosis
Systemic inflammatory response syndrome
X-Linked lymphoproliferative disease
url https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/462
work_keys_str_mv AT kgoudarzipour epsteinbarrvirusinducedhemophagocyticlymphohistiocytosis
AT mkajiyazdi epsteinbarrvirusinducedhemophagocyticlymphohistiocytosis
AT amahdaviyani epsteinbarrvirusinducedhemophagocyticlymphohistiocytosis