MAP3K7 and CHD1 Are Novel Mediators of Resistance to Oncolytic Vesicular Stomatitis Virus in Prostate Cancer Cells

A key principle of oncolytic viral therapy is that many cancers develop defects in their antiviral responses, making them more susceptible to virus infection. However, some cancers display resistance to viral infection. Many of these resistant cancers constitutively express interferon-stimulated gen...

Full description

Bibliographic Details
Main Authors: Robert S. Bayne, Shelby Puckett, Lindsey Ulkus Rodrigues, Scott D. Cramer, Jingyun Lee, Cristina M. Furdui, Jeff W. Chou, Lance D. Miller, David A. Ornelles, Douglas S. Lyles
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S237277052030067X