Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors
The purpose of this study was to compare fatigue, strength, body composition, muscle thickness, and muscle quality between Hodgkin’s lymphoma survivors (HLS) and apparently healthy subjects matched by age, gender, and physical activity levels (CON). Twelve HLS (32.16 ± 8.06) and 36 CON (32.42 ± 7.64...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2018-06-01
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| Series: | Integrative Cancer Therapies |
| Online Access: | https://doi.org/10.1177/1534735417712009 |
| _version_ | 1819026963257360384 |
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| author | Filipe Dinato de Lima MSc Martim Bottaro PhD Ritielli de Oliveira Valeriano MSc Lorena Cruz MSc Claudio L. Battaglini PhD, FACSM Carlos Alexandre Vieira PhD Ricardo Jacó de Oliveira PhD |
| author_facet | Filipe Dinato de Lima MSc Martim Bottaro PhD Ritielli de Oliveira Valeriano MSc Lorena Cruz MSc Claudio L. Battaglini PhD, FACSM Carlos Alexandre Vieira PhD Ricardo Jacó de Oliveira PhD |
| author_sort | Filipe Dinato de Lima MSc |
| collection | DOAJ |
| description | The purpose of this study was to compare fatigue, strength, body composition, muscle thickness, and muscle quality between Hodgkin’s lymphoma survivors (HLS) and apparently healthy subjects matched by age, gender, and physical activity levels (CON). Twelve HLS (32.16 ± 8.06) and 36 CON (32.42 ± 7.64) were enrolled in the study. Fatigue was assessed using the 20-item Multidimensional Fatigue Inventory, muscle strength using an isokinetic dynamometer, body composition using dual-energy X-ray absorptiometry, and thickness and muscle quality using B-mode ultrasound. Differences between HLS and CON were analyzed using independent samples t tests. No significant differences were observed between groups for any demographic characteristics: age ( P = .922), weight ( P = .943), height ( P = .511), body mass index ( P = .796), fat mass ( P = .688), fat-free mass ( P = .520), and percent body fat ( P = .446). No significant differences were observed for strength (peak torque; P = .552), relative peak torque ( P = .200), muscle thickness ( P > .05) and muscle quality ( P > .05). However, self-perceived fatigue was significantly higher in HLS than in CON ( P = .009). It appears that when HLS are matched by age and physical activity levels to CON, no significant difference in body composition, muscle thickness, muscle quality, or strength is observed. Self-perceived fatigue, as predicted, is higher in HLS, which may have implications and should be considered when prescribing exercise training to this cancer population. |
| first_indexed | 2024-12-21T05:34:55Z |
| format | Article |
| id | doaj.art-64fb4571f4f24fca9be7689295fc04bd |
| institution | Directory Open Access Journal |
| issn | 1534-7354 1552-695X |
| language | English |
| last_indexed | 2024-12-21T05:34:55Z |
| publishDate | 2018-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Integrative Cancer Therapies |
| spelling | doaj.art-64fb4571f4f24fca9be7689295fc04bd2022-12-21T19:14:27ZengSAGE PublishingIntegrative Cancer Therapies1534-73541552-695X2018-06-011710.1177/1534735417712009Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma SurvivorsFilipe Dinato de Lima MSc0Martim Bottaro PhD1Ritielli de Oliveira Valeriano MSc2Lorena Cruz MSc3Claudio L. Battaglini PhD, FACSM4Carlos Alexandre Vieira PhD5Ricardo Jacó de Oliveira PhD6University of Brasília, Brasília, BrazilUniversity of Brasília, Brasília, BrazilUniversity of Brasília, Brasília, BrazilUniversity of Brasília, Brasília, BrazilUniversity of North Carolina at Chapel Hill, NC, USAFederal University of Goiás, Goiania, BrazilUniversity of Brasília, Brasília, BrazilThe purpose of this study was to compare fatigue, strength, body composition, muscle thickness, and muscle quality between Hodgkin’s lymphoma survivors (HLS) and apparently healthy subjects matched by age, gender, and physical activity levels (CON). Twelve HLS (32.16 ± 8.06) and 36 CON (32.42 ± 7.64) were enrolled in the study. Fatigue was assessed using the 20-item Multidimensional Fatigue Inventory, muscle strength using an isokinetic dynamometer, body composition using dual-energy X-ray absorptiometry, and thickness and muscle quality using B-mode ultrasound. Differences between HLS and CON were analyzed using independent samples t tests. No significant differences were observed between groups for any demographic characteristics: age ( P = .922), weight ( P = .943), height ( P = .511), body mass index ( P = .796), fat mass ( P = .688), fat-free mass ( P = .520), and percent body fat ( P = .446). No significant differences were observed for strength (peak torque; P = .552), relative peak torque ( P = .200), muscle thickness ( P > .05) and muscle quality ( P > .05). However, self-perceived fatigue was significantly higher in HLS than in CON ( P = .009). It appears that when HLS are matched by age and physical activity levels to CON, no significant difference in body composition, muscle thickness, muscle quality, or strength is observed. Self-perceived fatigue, as predicted, is higher in HLS, which may have implications and should be considered when prescribing exercise training to this cancer population.https://doi.org/10.1177/1534735417712009 |
| spellingShingle | Filipe Dinato de Lima MSc Martim Bottaro PhD Ritielli de Oliveira Valeriano MSc Lorena Cruz MSc Claudio L. Battaglini PhD, FACSM Carlos Alexandre Vieira PhD Ricardo Jacó de Oliveira PhD Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors Integrative Cancer Therapies |
| title | Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors |
| title_full | Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors |
| title_fullStr | Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors |
| title_full_unstemmed | Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors |
| title_short | Cancer-Related Fatigue and Muscle Quality in Hodgkin’s Lymphoma Survivors |
| title_sort | cancer related fatigue and muscle quality in hodgkin s lymphoma survivors |
| url | https://doi.org/10.1177/1534735417712009 |
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