Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach
Background and study aims The light blue crest observed in narrow band imaging endoscopy has high diagnostic accuracy for diagnosis of gastric intestinal metaplasia (GIM). The objective of this prospective study was to evaluate the diagnostic accuracy of magnifying i-scan optical enhancement (OE) im...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2022-04-01
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| Series: | Endoscopy International Open |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/a-1759-2568 |
| _version_ | 1818059146464854016 |
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| author | Sergio Sobrino-Cossío Oscar Teramoto-Matsubara Fabian Emura Raúl Araya Vítor Arantes Elymir S. Galvis-García Marisi Meza-Caballero Blanca Sinahi García-Aguilar Arturo Reding-Bernal Noriya Uedo |
| author_facet | Sergio Sobrino-Cossío Oscar Teramoto-Matsubara Fabian Emura Raúl Araya Vítor Arantes Elymir S. Galvis-García Marisi Meza-Caballero Blanca Sinahi García-Aguilar Arturo Reding-Bernal Noriya Uedo |
| author_sort | Sergio Sobrino-Cossío |
| collection | DOAJ |
| description | Background and study aims The light blue crest observed in narrow band imaging endoscopy has high diagnostic accuracy for diagnosis of gastric intestinal metaplasia (GIM). The objective of this prospective study was to evaluate the diagnostic accuracy of magnifying i-scan optical enhancement (OE) imaging for diagnosing the LBC sign in patients with different levels of risk for gastric cancer in a Mexican clinical practice.
Patients and methods Patients with a history of peptic ulcer and symptoms of dyspepsia or gastroesophageal reflux disease were enrolled. Diagnosis of GIM was made at the predetermined anatomical location and white light endoscopy and i-scan OE Mode 1 were captured at the two predetermined biopsy sites (antrum and pyloric regions).
Results A total of 328 patients were enrolled in this study. Overall GIM prevalence was 33.8 %. The GIM distribution was 95.4 % in the antrum and 40.5 % in the corpus. According to the Operative Link on Gastritis/Intestinal-Metaplasia Assessment staging system, only two patients (1.9 %) were classified with high-risk stage disease. Sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios, and accuracy of both methods (95 % C. I.) were 0.50 (0.41–0.60), 0.55 (0.48–0.62), 0.36 (0.31–0.42), 0.68 (0.63–0.73), 1.12 (0.9–1.4), 0.9 (0.7–1.1), and 0.53 (0.43–0.60) for WLE, and 0.96 (0.90–0.99), 0.91 (0.86–0.94), 0.84 (0.78–0.89), 0.98 (0.94–0.99), 10.4 (6.8–16), 0.05 (0.02–0.12), and 0.93 (0.89–0.95), respectively. The kappa concordance was 0.67 and the reliability coefficient was 0.7407 for interobserver variability.
Conclusions Our study demonstrated the high performance of magnifying i-scan OE imaging for endoscopic diagnosis of GIM in Mexican patients. |
| first_indexed | 2024-12-10T13:11:53Z |
| format | Article |
| id | doaj.art-64fb48a9d23d48e39cd5384ce5c6afde |
| institution | Directory Open Access Journal |
| issn | 2364-3722 2196-9736 |
| language | English |
| last_indexed | 2024-12-10T13:11:53Z |
| publishDate | 2022-04-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Endoscopy International Open |
| spelling | doaj.art-64fb48a9d23d48e39cd5384ce5c6afde2022-12-22T01:47:39ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362022-04-011004E441E44710.1055/a-1759-2568Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomachSergio Sobrino-Cossío0Oscar Teramoto-Matsubara1Fabian Emura2Raúl Araya3Vítor Arantes4Elymir S. Galvis-García5Marisi Meza-Caballero6Blanca Sinahi García-Aguilar7Arturo Reding-Bernal8Noriya Uedo9Hospital Ángeles del Pedregal, Ciudad de Mexico, Mexico Gástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico Endoscopia Gastrointestinal Avanzada, EmuraCenter Latinoamérica y Departamento de Gastroenterología de la Universidad de la Sabana, Bogotá, Colombia Servicio de Endoscopia y Gastroenterología de la Clínica Universidad de Los Andes y del Hospital Militar de Santiago y Clínica Universidad de los Andes, Santiago, ChileHospital das Clínicas, Faculdade de Medicina, Universidade Federal de Minas Gerais, Hospital Mater Dei Contorno, Belo Horizonte, BrasilDepartment of Endoscopy. Hospital General de Mexico “Dr. Eduardo Liceaga,” Mexico City, MexicoGástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico Gástrica, Centro Avanzado en Endoscopia y Estudios Funcionales, Mexico City, Mexico Research Division, Hospital General de Mexico “Dr. Eduardo Liceaga,” Mexico City, MexicoOsaka International Cancer Institute, Department of Gastrointestinal Oncology, Osaka, JapanBackground and study aims The light blue crest observed in narrow band imaging endoscopy has high diagnostic accuracy for diagnosis of gastric intestinal metaplasia (GIM). The objective of this prospective study was to evaluate the diagnostic accuracy of magnifying i-scan optical enhancement (OE) imaging for diagnosing the LBC sign in patients with different levels of risk for gastric cancer in a Mexican clinical practice. Patients and methods Patients with a history of peptic ulcer and symptoms of dyspepsia or gastroesophageal reflux disease were enrolled. Diagnosis of GIM was made at the predetermined anatomical location and white light endoscopy and i-scan OE Mode 1 were captured at the two predetermined biopsy sites (antrum and pyloric regions). Results A total of 328 patients were enrolled in this study. Overall GIM prevalence was 33.8 %. The GIM distribution was 95.4 % in the antrum and 40.5 % in the corpus. According to the Operative Link on Gastritis/Intestinal-Metaplasia Assessment staging system, only two patients (1.9 %) were classified with high-risk stage disease. Sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios, and accuracy of both methods (95 % C. I.) were 0.50 (0.41–0.60), 0.55 (0.48–0.62), 0.36 (0.31–0.42), 0.68 (0.63–0.73), 1.12 (0.9–1.4), 0.9 (0.7–1.1), and 0.53 (0.43–0.60) for WLE, and 0.96 (0.90–0.99), 0.91 (0.86–0.94), 0.84 (0.78–0.89), 0.98 (0.94–0.99), 10.4 (6.8–16), 0.05 (0.02–0.12), and 0.93 (0.89–0.95), respectively. The kappa concordance was 0.67 and the reliability coefficient was 0.7407 for interobserver variability. Conclusions Our study demonstrated the high performance of magnifying i-scan OE imaging for endoscopic diagnosis of GIM in Mexican patients.http://www.thieme-connect.de/DOI/DOI?10.1055/a-1759-2568 |
| spellingShingle | Sergio Sobrino-Cossío Oscar Teramoto-Matsubara Fabian Emura Raúl Araya Vítor Arantes Elymir S. Galvis-García Marisi Meza-Caballero Blanca Sinahi García-Aguilar Arturo Reding-Bernal Noriya Uedo Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach Endoscopy International Open |
| title | Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach |
| title_full | Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach |
| title_fullStr | Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach |
| title_full_unstemmed | Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach |
| title_short | Usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach |
| title_sort | usefulness of optical enhancement endoscopy combined with magnification to improve detection of intestinal metaplasia in the stomach |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/a-1759-2568 |
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