Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

How astrocytes influence neuronal plasticity remains unclear, as they are typically considered as modulators of core mechanisms driven by neuronal components. Here, authors show that Long-term depression (LTD) induction in the hippocampus triggers calcium signaling in the astrocyte and enhances SNAR...

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Bibliographic Details
Main Authors: Marta Navarrete, María I. Cuartero, Rocío Palenzuela, Jonathan E. Draffin, Ainoa Konomi, Irene Serra, Sandra Colié, Sergio Castaño-Castaño, Mazahir T. Hasan, Ángel R. Nebreda, José A. Esteban
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10830-9

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