Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination
This article reviews the literature on SARS-CoV-2 pandemic and multiple sclerosis (MS). The first part of the paper focuses on the current data on immunopathology of SARS-CoV-2 and leading vaccines produced against COVID-19 infection. In the second part of the article, we discuss the effect of Disea...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/10/2/279 |
| _version_ | 1797476122822180864 |
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| author | Maryam Golshani Jiří Hrdý |
| author_facet | Maryam Golshani Jiří Hrdý |
| author_sort | Maryam Golshani |
| collection | DOAJ |
| description | This article reviews the literature on SARS-CoV-2 pandemic and multiple sclerosis (MS). The first part of the paper focuses on the current data on immunopathology of SARS-CoV-2 and leading vaccines produced against COVID-19 infection. In the second part of the article, we discuss the effect of Disease Modifying Therapies (DMTs) on COVID-19 infection severity or SARS-CoV-2 vaccination in MS patients plus safety profile of different vaccine platforms in MS patients. |
| first_indexed | 2024-03-09T20:53:32Z |
| format | Article |
| id | doaj.art-65075fa8741445d1bb4ae2906edbf66b |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T20:53:32Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-65075fa8741445d1bb4ae2906edbf66b2023-11-23T22:26:26ZengMDPI AGVaccines2076-393X2022-02-0110227910.3390/vaccines10020279Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 VaccinationMaryam Golshani0Jiří Hrdý1Institute of Immunology and Microbiology, Faculty of Medicine, Charles University, 128 00 Prague, Czech RepublicInstitute of Immunology and Microbiology, Faculty of Medicine, Charles University, 128 00 Prague, Czech RepublicThis article reviews the literature on SARS-CoV-2 pandemic and multiple sclerosis (MS). The first part of the paper focuses on the current data on immunopathology of SARS-CoV-2 and leading vaccines produced against COVID-19 infection. In the second part of the article, we discuss the effect of Disease Modifying Therapies (DMTs) on COVID-19 infection severity or SARS-CoV-2 vaccination in MS patients plus safety profile of different vaccine platforms in MS patients.https://www.mdpi.com/2076-393X/10/2/279SARS-CoV-2COVID-19multiple sclerosisDMTsimmunosuppressionvaccine |
| spellingShingle | Maryam Golshani Jiří Hrdý Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination Vaccines SARS-CoV-2 COVID-19 multiple sclerosis DMTs immunosuppression vaccine |
| title | Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination |
| title_full | Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination |
| title_fullStr | Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination |
| title_full_unstemmed | Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination |
| title_short | Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination |
| title_sort | multiple sclerosis patients and disease modifying therapies impact on immune responses against covid 19 and sars cov 2 vaccination |
| topic | SARS-CoV-2 COVID-19 multiple sclerosis DMTs immunosuppression vaccine |
| url | https://www.mdpi.com/2076-393X/10/2/279 |
| work_keys_str_mv | AT maryamgolshani multiplesclerosispatientsanddiseasemodifyingtherapiesimpactonimmuneresponsesagainstcovid19andsarscov2vaccination AT jirihrdy multiplesclerosispatientsanddiseasemodifyingtherapiesimpactonimmuneresponsesagainstcovid19andsarscov2vaccination |