Transcriptomics of CD29+/CD44+ cells isolated from hPSC retinal organoids reveals a single cell population with retinal progenitor and Müller glia characteristics
Abstract Müller glia play very important and diverse roles in retinal homeostasis and disease. Although much is known of the physiological and morphological properties of mammalian Müller glia, there is still the need to further understand the profile of these cells during human retinal development....
Main Authors: | Karen Eastlake, Joshua Luis, Weixin Wang, William Lamb, Peng T. Khaw, G. Astrid Limb |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-32058-w |
Similar Items
-
Organoid-derived human retinal progenitor cells promote early dedifferentiation of Müller glia in Royal College of Surgeons rats
by: Qiang Guo, et al.
Published: (2023-04-01) -
hPSC-derived lung organoids: Potential opportunities and challenges
by: Xiaoli Du, et al.
Published: (2023-02-01) -
Human pluripotent stem cell (hPSC) and organoid models of autism: opportunities and limitations
by: Savannah Kilpatrick, et al.
Published: (2023-06-01) -
Müller Glia in Retinal Development: From Specification to Circuit Integration
by: Joshua M. Tworig, et al.
Published: (2022-02-01) -
Translatomic response of retinal Müller glia to acute and chronic stress
by: Ana J. Chucair-Elliott, et al.
Published: (2022-12-01)