Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors
HIV-1 infects 39.5 million people worldwide, and cART is effective in preventing viral spread by reducing HIV-1 plasma viral loads to undetectable levels. However, viral reservoirs persist by mechanisms, including the inhibition of autophagy by HIV-1 proteins (i.e., Nef and Tat). HIV-1 reservoirs ca...
Main Authors: | Daniel O. Pinto, Catherine DeMarino, Thy T. Vo, Maria Cowen, Yuriy Kim, Michelle L. Pleet, Robert A. Barclay, Nicole Noren Hooten, Michele K. Evans, Alonso Heredia, Elena V. Batrakova, Sergey Iordanskiy, Fatah Kashanchi |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/12/8/885 |
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