Metabolic disorders sensitise endometrial carcinoma through endoplasmic reticulum stress

Metabolic disorders sensitise endometrial carcinoma through endoplasmic reticulum stress

Abstract Background Metabolic disorder is considered a well-established risk factor for endometrial carcinoma (EC). However, the mechanism remains unclear. Insulin resistance and excessive flux of free fatty acids serve as fundamental pathogenic factors in metabolic disorders, including obesity and...

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Bibliographic Details
Main Authors: Jingyi Zhou, Yanying Lin, Xiao Yang, Boqiang Shen, Juan Hao, Jiaqi Wang, Jianliu Wang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
Endometrial carcinoma
Metabolic disorders
Insulin
Endoplasmic reticulum stress
Saturated fatty acid
Online Access:https://doi.org/10.1186/s11658-022-00412-x

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