Neurogranin regulates eNOS function and endothelial activation

Neurogranin regulates eNOS function and endothelial activation

Endothelial nitric oxide (NO) is a critical mediator of vascular function and vascular remodeling. NO is produced by endothelial nitric oxide synthase (eNOS), which is activated by calcium (Ca2+)-dependent and Ca2+-independent pathways. Here, we report that neurogranin (Ng), which regulates Ca2+-cal...

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Bibliographic Details
Main Authors: Vino T. Cheriyan, Mabruka Alfaidi, Ashton N. Jorgensen, Md Ashiqul Alam, Chowdhury S. Abdullah, Gopi K. Kolluru, Md Shenuarin Bhuiyan, Christopher G. Kevil, A. Wayne Orr, Hyung W. Nam
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Oxidative stress
Nitric oxide
Endothelial dysfunction
Neurogranin
Shear stress
Flow-mediated dilation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720301919

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http://www.sciencedirect.com/science/article/pii/S2213231720301919

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