Structures suggest a mechanism for energy coupling by a family of organic anion transporters.

Structures suggest a mechanism for energy coupling by a family of organic anion transporters.

Members of the solute carrier 17 (SLC17) family use divergent mechanisms to concentrate organic anions. Membrane potential drives uptake of the principal excitatory neurotransmitter glutamate into synaptic vesicles, whereas closely related proteins use proton cotransport to drive efflux from the lys...

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Bibliographic Details
Main Authors: Jonathan B Leano, Samir Batarni, Jacob Eriksen, Narinobu Juge, John E Pak, Tomomi Kimura-Someya, Yaneth Robles-Colmenares, Yoshinori Moriyama, Robert M Stroud, Robert H Edwards
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000260

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https://doi.org/10.1371/journal.pbio.3000260

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