Dexmedetomidine protects H9c2 cardiomyocytes against oxygen-glucose deprivation/reoxygenation-induced intracellular calcium overload and apoptosis through regulating FKBP12.6/RyR2 signaling

Dexmedetomidine protects H9c2 cardiomyocytes against oxygen-glucose deprivation/reoxygenation-induced intracellular calcium overload and apoptosis through regulating FKBP12.6/RyR2 signaling

Mei Yuan,1,2,* Xiao-Wen Meng,1,* Jiao Ma,1,* Hong Liu,3 Shao-Yong Song,1 Qing-Cai Chen,1 Hua-Yue Liu,1 Juan Zhang,1 Nan Song,1 Fu-Hai Ji,1 Ke Peng11Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, People’s Republic of China; 2Department...

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Bibliographic Details
Main Authors: Yuan M, Meng XW, Ma J, Liu H, Song SY, Chen QC, Liu HY, Zhang J, Song N, Ji FH, Peng K
Format: Article
Language:English
Published: Dove Medical Press 2019-09-01
Series:Drug Design, Development and Therapy
Subjects:
dexmedetomidine
H9c2 cardiomyocytes
oxygen-glucose deprivation/reoxygenation
apoptosis
intracellular calcium overload
FKBP12.6/RyR2
Online Access:https://www.dovepress.com/dexmedetomidine-protects-h9c2-cardiomyocytes-against-oxygen-glucose-de-peer-reviewed-article-DDDT

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https://www.dovepress.com/dexmedetomidine-protects-h9c2-cardiomyocytes-against-oxygen-glucose-de-peer-reviewed-article-DDDT

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