Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis

Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis

Abstract Extracellular vesicles (EVs) exert a significant influence not only on the pathogenesis of diseases but also on their therapeutic interventions, contingent upon the variances observed in their originating cells. Mitochondria can be transported between cells via EVs to promote pathological c...

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Bibliographic Details
Main Authors: Yuhua Gao, Ningning Mi, Wenxiang Wu, Yuxuan Zhao, Fangzhou Fan, Wangwei Liao, Yongliang Ming, Weijun Guan, Chunyu Bai
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
ferroptosis
M1 macrophages
mitochondria
pancreatic beta cells
Online Access:https://doi.org/10.1002/jev2.12410

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