Is DNA methylation of tumour suppressor genes epigenetic?
In colorectal cancer cells, a non-epigenetic transcriptional pathway that is mediated by an oncogene maintains DNA methylation of tumour suppressor genes
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2014-03-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/02475 |
| _version_ | 1818018930207227904 |
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| author | Kevin Struhl |
| author_facet | Kevin Struhl |
| author_sort | Kevin Struhl |
| collection | DOAJ |
| description | In colorectal cancer cells, a non-epigenetic transcriptional pathway that is mediated by an oncogene maintains DNA methylation of tumour suppressor genes |
| first_indexed | 2024-04-14T07:46:01Z |
| format | Article |
| id | doaj.art-652552c3889d493a99b69d2b8dc7156c |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-14T07:46:01Z |
| publishDate | 2014-03-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-652552c3889d493a99b69d2b8dc7156c2022-12-22T02:05:20ZengeLife Sciences Publications LtdeLife2050-084X2014-03-01310.7554/eLife.02475Is DNA methylation of tumour suppressor genes epigenetic?Kevin Struhl0Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United StatesIn colorectal cancer cells, a non-epigenetic transcriptional pathway that is mediated by an oncogene maintains DNA methylation of tumour suppressor geneshttps://elifesciences.org/articles/02475CpG island methylator phenotypeINK4-ARFcolorectal cancerZNF304KRASDNMT1 |
| spellingShingle | Kevin Struhl Is DNA methylation of tumour suppressor genes epigenetic? eLife CpG island methylator phenotype INK4-ARF colorectal cancer ZNF304 KRAS DNMT1 |
| title | Is DNA methylation of tumour suppressor genes epigenetic? |
| title_full | Is DNA methylation of tumour suppressor genes epigenetic? |
| title_fullStr | Is DNA methylation of tumour suppressor genes epigenetic? |
| title_full_unstemmed | Is DNA methylation of tumour suppressor genes epigenetic? |
| title_short | Is DNA methylation of tumour suppressor genes epigenetic? |
| title_sort | is dna methylation of tumour suppressor genes epigenetic |
| topic | CpG island methylator phenotype INK4-ARF colorectal cancer ZNF304 KRAS DNMT1 |
| url | https://elifesciences.org/articles/02475 |
| work_keys_str_mv | AT kevinstruhl isdnamethylationoftumoursuppressorgenesepigenetic |