Tumor Restrictions to Oncolytic Virus

Tumor Restrictions to Oncolytic Virus

Oncolytic virotherapy has advanced since the days of its conception but therapeutic efficacy in the clinics does not seem to reach the same level as in animal models. One reason is premature oncolytic virus clearance in humans, which is a reasonable assumption considering the immune-stimulating natu...

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Bibliographic Details
Main Authors:	Markus Vähä-Koskela, Ari Hinkkanen
Format:	Article
Language:	English
Published:	MDPI AG 2014-04-01
Series:	Biomedicines
Subjects:	oncolytic virus interferon tumor stroma antiviral defenses extracellular matrix tight junctions
Online Access:	http://www.mdpi.com/2227-9059/2/2/163

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