A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual
Background: No vaccine is 100% effective in prevention of infection. The possibility of breakthrough infection of SARS-CoV-2 also cannot be ruled out. So, our study aimed to find out severity and risk of breakthrough infection and find association between epidemiological factors associated with it....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=9;spage=2024;epage=2027;aulast=Dhoble |
| _version_ | 1797645639952105472 |
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| author | Shital Dhoble Devishri Atram Niwrutti Jiwane Anil Naitam |
| author_facet | Shital Dhoble Devishri Atram Niwrutti Jiwane Anil Naitam |
| author_sort | Shital Dhoble |
| collection | DOAJ |
| description | Background: No vaccine is 100% effective in prevention of infection. The possibility of breakthrough infection of SARS-CoV-2 also cannot be ruled out. So, our study aimed to find out severity and risk of breakthrough infection and find association between epidemiological factors associated with it. Methodology: A retrospective cross-sectional study was conducted on 148 admitted SARS-CoV-2 vaccinated individual from May 2021 to January 2022 by universal sampling method. A data was collected in the form of socio-demographic, Covid vaccine, clinical details, and outcome of admitted patients. An appropriate statistical test was applied. Results: Out of the total 148 vaccinated individuals, 66 (44.59%) belongs to 30–59 years of age group and maximum, i.e. 95 (64.19%) were males. 64.86% patients were vaccinated with both doses and 98 (66.26%) individuals were mild cases. Only 8 (5.40%) cases were re-infected with Covid-19 infection. 70.27% individual were comorbid. Out of 148 vaccinated individuals, only 11 (7.43%) individuals were died and among those 7 (63.636%) were comorbid. Conclusion: Despite being vaccinated, small percentage of people are still getting infected, requires hospitalization, and die because of COVID-19. As far as pandemic continues, continuous genome sequencing and tracking of SARS-CoV-2 is essential and strategies regarding vaccination should be adjusted accordingly. |
| first_indexed | 2024-03-11T14:49:41Z |
| format | Article |
| id | doaj.art-652599ba4b454e8ba6dcd5c3bce579ca |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-03-11T14:49:41Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-652599ba4b454e8ba6dcd5c3bce579ca2023-10-30T09:46:32ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632023-01-011292024202710.4103/jfmpc.jfmpc_485_23A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individualShital DhobleDevishri AtramNiwrutti JiwaneAnil NaitamBackground: No vaccine is 100% effective in prevention of infection. The possibility of breakthrough infection of SARS-CoV-2 also cannot be ruled out. So, our study aimed to find out severity and risk of breakthrough infection and find association between epidemiological factors associated with it. Methodology: A retrospective cross-sectional study was conducted on 148 admitted SARS-CoV-2 vaccinated individual from May 2021 to January 2022 by universal sampling method. A data was collected in the form of socio-demographic, Covid vaccine, clinical details, and outcome of admitted patients. An appropriate statistical test was applied. Results: Out of the total 148 vaccinated individuals, 66 (44.59%) belongs to 30–59 years of age group and maximum, i.e. 95 (64.19%) were males. 64.86% patients were vaccinated with both doses and 98 (66.26%) individuals were mild cases. Only 8 (5.40%) cases were re-infected with Covid-19 infection. 70.27% individual were comorbid. Out of 148 vaccinated individuals, only 11 (7.43%) individuals were died and among those 7 (63.636%) were comorbid. Conclusion: Despite being vaccinated, small percentage of people are still getting infected, requires hospitalization, and die because of COVID-19. As far as pandemic continues, continuous genome sequencing and tracking of SARS-CoV-2 is essential and strategies regarding vaccination should be adjusted accordingly.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=9;spage=2024;epage=2027;aulast=Dhoblebreakthrough infectioneffectiveepidemiological factorspandemicsars-cov-2tracking |
| spellingShingle | Shital Dhoble Devishri Atram Niwrutti Jiwane Anil Naitam A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual Journal of Family Medicine and Primary Care breakthrough infection effective epidemiological factors pandemic sars-cov-2 tracking |
| title | A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual |
| title_full | A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual |
| title_fullStr | A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual |
| title_full_unstemmed | A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual |
| title_short | A study to assess the severity and risk of COVID-19 breakthrough infection in admitted SARS-CoV-2 vaccinated individual |
| title_sort | study to assess the severity and risk of covid 19 breakthrough infection in admitted sars cov 2 vaccinated individual |
| topic | breakthrough infection effective epidemiological factors pandemic sars-cov-2 tracking |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=9;spage=2024;epage=2027;aulast=Dhoble |
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