The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson’s Disease-Associated Neurodegeneration

The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson’s Disease-Associated Neurodegeneration

The degeneration of midbrain dopaminergic (mDA) neurons, particularly in the substantia nigra pars compacta (SNc), is one of the most prominent pathological hallmarks of Parkinson’s disease (PD). To uncover the pathogenic mechanisms of mDA neuronal death during PD may provide therapeutic targets to...

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Bibliographic Details
Main Authors:	Xin Wang, Xi Chen, Guangdong Liu, Huaibin Cai, Weidong Le
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	International Journal of Molecular Sciences
Subjects:	Parkinson’s disease paired-like homeodomain transcription factor 3 (Pitx3) midbrain dopaminergic neuron development transcription factors
Online Access:	https://www.mdpi.com/1422-0067/24/10/8614

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