Unravelling cell migration: defining movement from the cell surface
Cell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors. Cells change their migratory strategy based on their phenotype and the properties of the su...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-12-01
|
| Series: | Cell Adhesion & Migration |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19336918.2022.2055520 |
| _version_ | 1811291996117008384 |
|---|---|
| author | Francisco Merino-Casallo Maria Jose Gomez-Benito Silvia Hervas-Raluy Jose Manuel Garcia-Aznar |
| author_facet | Francisco Merino-Casallo Maria Jose Gomez-Benito Silvia Hervas-Raluy Jose Manuel Garcia-Aznar |
| author_sort | Francisco Merino-Casallo |
| collection | DOAJ |
| description | Cell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors. Cells change their migratory strategy based on their phenotype and the properties of the surrounding microenvironment. Cell migration is, therefore, an extremely complex phenomenon. Researchers have investigated cell motility for more than a century. Recent discoveries have uncovered some of the mysteries associated with the mechanisms involved in cell migration, such as intracellular signaling and cell mechanics. These findings involve different players, including transmembrane receptors, adhesive complexes, cytoskeletal components , the nucleus, and the extracellular matrix. This review aims to give a global overview of our current understanding of cell migration. |
| first_indexed | 2024-04-13T04:38:50Z |
| format | Article |
| id | doaj.art-652ea42220a04717937c7e7e7c734f60 |
| institution | Directory Open Access Journal |
| issn | 1933-6918 1933-6926 |
| language | English |
| last_indexed | 2024-04-13T04:38:50Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Cell Adhesion & Migration |
| spelling | doaj.art-652ea42220a04717937c7e7e7c734f602022-12-22T03:02:05ZengTaylor & Francis GroupCell Adhesion & Migration1933-69181933-69262022-12-01161256410.1080/19336918.2022.2055520Unravelling cell migration: defining movement from the cell surfaceFrancisco Merino-Casallo0Maria Jose Gomez-Benito1Silvia Hervas-Raluy2Jose Manuel Garcia-Aznar3Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), Zaragoza, SpainMultiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), Zaragoza, SpainMultiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), Zaragoza, SpainMultiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), Zaragoza, SpainCell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors. Cells change their migratory strategy based on their phenotype and the properties of the surrounding microenvironment. Cell migration is, therefore, an extremely complex phenomenon. Researchers have investigated cell motility for more than a century. Recent discoveries have uncovered some of the mysteries associated with the mechanisms involved in cell migration, such as intracellular signaling and cell mechanics. These findings involve different players, including transmembrane receptors, adhesive complexes, cytoskeletal components , the nucleus, and the extracellular matrix. This review aims to give a global overview of our current understanding of cell migration.https://www.tandfonline.com/doi/10.1080/19336918.2022.2055520Cell migrationcell mechanicsextracellular matrix |
| spellingShingle | Francisco Merino-Casallo Maria Jose Gomez-Benito Silvia Hervas-Raluy Jose Manuel Garcia-Aznar Unravelling cell migration: defining movement from the cell surface Cell Adhesion & Migration Cell migration cell mechanics extracellular matrix |
| title | Unravelling cell migration: defining movement from the cell surface |
| title_full | Unravelling cell migration: defining movement from the cell surface |
| title_fullStr | Unravelling cell migration: defining movement from the cell surface |
| title_full_unstemmed | Unravelling cell migration: defining movement from the cell surface |
| title_short | Unravelling cell migration: defining movement from the cell surface |
| title_sort | unravelling cell migration defining movement from the cell surface |
| topic | Cell migration cell mechanics extracellular matrix |
| url | https://www.tandfonline.com/doi/10.1080/19336918.2022.2055520 |
| work_keys_str_mv | AT franciscomerinocasallo unravellingcellmigrationdefiningmovementfromthecellsurface AT mariajosegomezbenito unravellingcellmigrationdefiningmovementfromthecellsurface AT silviahervasraluy unravellingcellmigrationdefiningmovementfromthecellsurface AT josemanuelgarciaaznar unravellingcellmigrationdefiningmovementfromthecellsurface |