Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments

Tomographic diffractive microscopy (TDM) is a label-free, far-field, super-resolution microscope. The significant difference between TDM and wide-field microscopy is that in TDM the sample is illuminated from various directions with a coherent collimated beam and the complex diffracted field is coll...

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Main Authors: Ting Zhang, Kan Li, Charankumar Godavarthi, Yi Ruan
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/9/18/3834
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author Ting Zhang
Kan Li
Charankumar Godavarthi
Yi Ruan
author_facet Ting Zhang
Kan Li
Charankumar Godavarthi
Yi Ruan
author_sort Ting Zhang
collection DOAJ
description Tomographic diffractive microscopy (TDM) is a label-free, far-field, super-resolution microscope. The significant difference between TDM and wide-field microscopy is that in TDM the sample is illuminated from various directions with a coherent collimated beam and the complex diffracted field is collected from many scattered angles. By utilizing inversion procedures, the permittivity/refractive index of investigated samples can be retrieved from the measured diffracted field to reconstruct the geometrical parameters of a sample. TDM opens up new opportunities to study biological samples and nano-structures and devices, which require resolution beyond the Rayleigh limit. In this review, we describe the principles and recent advancements of TDM and also give the perspectives of this fantastic microscopy technique.
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spelling doaj.art-652ee8e5c38344d2a4d28712c0fcf0e12022-12-22T01:45:49ZengMDPI AGApplied Sciences2076-34172019-09-01918383410.3390/app9183834app9183834Tomographic Diffractive Microscopy: A Review of Methods and Recent DevelopmentsTing Zhang0Kan Li1Charankumar Godavarthi2Yi Ruan3Zhejiang Provincial Key Laboratory of Information Processing, Communication and Networking (IPCN), College of Information Science & Electronic Engineering, Zhejiang University, Hangzhou 310027, ChinaCollaborative Innovation Center for Bio-Med Physics Information Technology, College of Science, Zhejiang University of Technology, Hangzhou 310014, ChinaRue de l’hostellerie-Ville active, 30900 Nimes, FranceCollaborative Innovation Center for Bio-Med Physics Information Technology, College of Science, Zhejiang University of Technology, Hangzhou 310014, ChinaTomographic diffractive microscopy (TDM) is a label-free, far-field, super-resolution microscope. The significant difference between TDM and wide-field microscopy is that in TDM the sample is illuminated from various directions with a coherent collimated beam and the complex diffracted field is collected from many scattered angles. By utilizing inversion procedures, the permittivity/refractive index of investigated samples can be retrieved from the measured diffracted field to reconstruct the geometrical parameters of a sample. TDM opens up new opportunities to study biological samples and nano-structures and devices, which require resolution beyond the Rayleigh limit. In this review, we describe the principles and recent advancements of TDM and also give the perspectives of this fantastic microscopy technique.https://www.mdpi.com/2076-3417/9/18/3834tomographic diffractive microscopy (TDM)diffracted fieldholographic interferometryinverse scattering
spellingShingle Ting Zhang
Kan Li
Charankumar Godavarthi
Yi Ruan
Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments
Applied Sciences
tomographic diffractive microscopy (TDM)
diffracted field
holographic interferometry
inverse scattering
title Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments
title_full Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments
title_fullStr Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments
title_full_unstemmed Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments
title_short Tomographic Diffractive Microscopy: A Review of Methods and Recent Developments
title_sort tomographic diffractive microscopy a review of methods and recent developments
topic tomographic diffractive microscopy (TDM)
diffracted field
holographic interferometry
inverse scattering
url https://www.mdpi.com/2076-3417/9/18/3834
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AT yiruan tomographicdiffractivemicroscopyareviewofmethodsandrecentdevelopments