VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells

VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells

Summary: The formation of new vessels requires a tight synchronization between proliferation, differentiation, and sprouting. However, how these processes are differentially activated, often by neighboring endothelial cells (ECs), remains unclear. Here, we identify cell cycle progression as a regula...

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Bibliographic Details
Main Authors: Ayelet Jerafi-Vider, Ivan Bassi, Noga Moshe, Yaara Tevet, Gideon Hen, Daniel Splittstoesser, Masahiro Shin, Nathan D. Lawson, Karina Yaniv
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721006203

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