Metabolism, HDACs, and HDAC Inhibitors: A Systems Biology Perspective

Histone deacetylases (HDACs) are epigenetic enzymes that play a central role in gene regulation and are sensitive to the metabolic state of the cell. The cross talk between metabolism and histone acetylation impacts numerous biological processes including development and immune function. HDAC inhibi...

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Bibliographic Details
Main Authors: Jacob King, Maya Patel, Sriram Chandrasekaran
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/11/792