THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH
Background: Coagulation abnormalities has been reported in patients with impaired metabolism of thyroid hormones. Platelets play an important role in coagulation and Mean Platelet Volume has been considered as an inflammatory biomarker in multiple diseases. Objectives: The aim of this study was to...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Rabia Yılmaz
2022-03-01
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| Series: | Journal of Contemporary Medicine |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1748501 |
| _version_ | 1797860618092412928 |
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| author | Hilal Aksoy Mine Öztürk |
| author_facet | Hilal Aksoy Mine Öztürk |
| author_sort | Hilal Aksoy |
| collection | DOAJ |
| description | Background: Coagulation abnormalities has been reported in patients with impaired metabolism of thyroid hormones. Platelets play an important role in coagulation and Mean Platelet Volume has been considered as an inflammatory biomarker in multiple diseases.
Objectives: The aim of this study was to investigate whether any relationship exists between the values of thyroid-stimulating hormone, free thyroxine, anti-thyroid peroxidase, anti-thyroglobulin and those of the MPV.
Methods: Patients who were admitted to the Endocrinology outpatient clinic between October 2013 and July 2019 with a pre-diagnosis of thyroid disease were included in the study. The data were analyzed with IBM SPSS V23. Compatibility with normal distribution was examined with the Shapiro Wilk test. The relation between the variables was evaluated with Spearman rank correlation.
Results: Records of 1098 patients were examined. There is a very weak positive relationship between TSH and MPV (r: 0,075), there is no significant relationship between ST4, Anti TPO, Anti TG and MPV.
Conclusion: Patients have high TSH values display a increased MPV should hence be acknowledged in risk prediction of thrombotic events. |
| first_indexed | 2024-04-09T21:48:46Z |
| format | Article |
| id | doaj.art-6538a0f13fa847edbc00285eaf109705 |
| institution | Directory Open Access Journal |
| issn | 2667-7180 |
| language | English |
| last_indexed | 2024-04-09T21:48:46Z |
| publishDate | 2022-03-01 |
| publisher | Rabia Yılmaz |
| record_format | Article |
| series | Journal of Contemporary Medicine |
| spelling | doaj.art-6538a0f13fa847edbc00285eaf1097052023-03-24T19:43:26ZengRabia YılmazJournal of Contemporary Medicine2667-71802022-03-0112236937210.16899/jcm.9320531809THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCHHilal Aksoy0Mine Öztürk1Hacettepe Üniversitesi Tıp Fakültesi, Aile Hekimliği Anabilim DalıKTO KARATAY ÜNİVERSİTESİBackground: Coagulation abnormalities has been reported in patients with impaired metabolism of thyroid hormones. Platelets play an important role in coagulation and Mean Platelet Volume has been considered as an inflammatory biomarker in multiple diseases. Objectives: The aim of this study was to investigate whether any relationship exists between the values of thyroid-stimulating hormone, free thyroxine, anti-thyroid peroxidase, anti-thyroglobulin and those of the MPV. Methods: Patients who were admitted to the Endocrinology outpatient clinic between October 2013 and July 2019 with a pre-diagnosis of thyroid disease were included in the study. The data were analyzed with IBM SPSS V23. Compatibility with normal distribution was examined with the Shapiro Wilk test. The relation between the variables was evaluated with Spearman rank correlation. Results: Records of 1098 patients were examined. There is a very weak positive relationship between TSH and MPV (r: 0,075), there is no significant relationship between ST4, Anti TPO, Anti TG and MPV. Conclusion: Patients have high TSH values display a increased MPV should hence be acknowledged in risk prediction of thrombotic events.https://dergipark.org.tr/tr/download/article-file/1748501thyroid hormonesmean platelet volumethyroid diseasetiroid hormonlarıortalama trombosit hacmitiroid hastalığı |
| spellingShingle | Hilal Aksoy Mine Öztürk THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH Journal of Contemporary Medicine thyroid hormones mean platelet volume thyroid disease tiroid hormonları ortalama trombosit hacmi tiroid hastalığı |
| title | THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH |
| title_full | THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH |
| title_fullStr | THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH |
| title_full_unstemmed | THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH |
| title_short | THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH |
| title_sort | effects of thyroid stimulating hormone free thyroxine levels and thyroid antibodies on mean platelet volume original research |
| topic | thyroid hormones mean platelet volume thyroid disease tiroid hormonları ortalama trombosit hacmi tiroid hastalığı |
| url | https://dergipark.org.tr/tr/download/article-file/1748501 |
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