Human Renal Fibroblasts, but Not Renal Epithelial Cells, Induce IL-1β Release during a Uropathogenic <i>Escherichia coli</i> Infection In Vitro

Human Renal Fibroblasts, but Not Renal Epithelial Cells, Induce IL-1β Release during a Uropathogenic <i>Escherichia coli</i> Infection In Vitro

Understanding how uropathogenic <i>Escherichia coli</i> (UPEC) modulates the immune response in the kidney is essential to prevent UPEC from reaching the bloodstream and causing urosepsis. The purpose of this study was to elucidate if renal fibroblasts can release IL-1β during a UPEC inf...

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Bibliographic Details
Main Authors: Ashok Kumar Kumawat, Geena Varghese Paramel, Kartheyaene Jayaprakash Demirel, Isak Demirel
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
UPEC
human renal fibroblasts
inflammasome
UTI
IL-1β
Online Access:https://www.mdpi.com/2073-4409/10/12/3522

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