Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila

Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila

Naturally produced peptides (<100 amino acids) are important regulators of physiology, development, and metabolism. Recent studies have predicted that thousands of peptides may be translated from transcripts containing small open-reading frames (smORFs). Here, we describe two peptides in Dros...

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Bibliographic Details
Main Authors: Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-11-01
Series:eLife
Subjects:
smORF
peptide
mitochondria
neurodegeneration
CRISPR/Cas9
paralogs
Online Access:https://elifesciences.org/articles/82709

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