Bayes factors for superiority, non-inferiority, and equivalence designs

Bayes factors for superiority, non-inferiority, and equivalence designs

Abstract Background In clinical trials, study designs may focus on assessment of superiority, equivalence, or non-inferiority, of a new medicine or treatment as compared to a control. Typically, evidence in each of these paradigms is quantified with a variant of the null hypothesis significance test...

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Bibliographic Details
Main Authors: Don van Ravenzwaaij, Rei Monden, Jorge N. Tendeiro, John P. A. Ioannidis
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Medical Research Methodology
Subjects:
Bayes factors
Clinical trials
Statistical inference
Non-inferiority designs
Online Access:http://link.springer.com/article/10.1186/s12874-019-0699-7

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