Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis

Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis

Airway inflammation and microbiome dysbiosis are hallmarks of cystic fibrosis (CF) lung disease. However, longitudinal studies are needed to decipher which factors contribute to the long-term evolution of these key features of CF. We therefore evaluated the relationship between fluctuation in microb...

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Bibliographic Details
Main Authors: Dario L. Frey, Calum Bridson, Susanne Dittrich, Simon Y. Graeber, Mirjam Stahl, Sabine Wege, Felix Herth, Olaf Sommerburg, Carsten Schultz, Alexander Dalpke, Marcus A. Mall, Sébastien Boutin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
microbiome
cystic fibrosis
16S rRNA gene
inflammation
longitudinal study
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.885822/full

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