Statin Exposure and Risk of Heart Failure After Anthracycline‐ or Trastuzumab‐Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study

Statin Exposure and Risk of Heart Failure After Anthracycline‐ or Trastuzumab‐Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study

Background Statins are hypothesized to reduce the risk of cardiotoxicity associated with anthracyclines and trastuzumab. Our aim was to study the association of statin exposure with hospitalization or emergency department visits (hospital presentations) for heart failure (HF) after anthracycline‐ an...

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Bibliographic Details
Main Authors: Husam Abdel‐Qadir, David Bobrowski, Limei Zhou, Peter C. Austin, Oscar Calvillo‐Argüelles, Eitan Amir, Douglas S. Lee, Paaladinesh Thavendiranathan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
anthracycline
cardiotoxicity
heart failure
statin
trastuzumab
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.018393

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