Inhibition of Urease by Disulfiram, an FDA-Approved Thiol Reagent Used in Humans

Inhibition of Urease by Disulfiram, an FDA-Approved Thiol Reagent Used in Humans

Urease is a nickel-dependent amidohydrolase that catalyses the decomposition of urea into carbamate and ammonia, a reaction that constitutes an important source of nitrogen for bacteria, fungi and plants. It is recognized as a potential antimicrobial target with an impact on medicine, agriculture, a...

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Bibliographic Details
Main Authors: Ángel Gabriel Díaz-Sánchez, Emilio Alvarez-Parrilla, Alejandro Martínez-Martínez, Luis Aguirre-Reyes, Jesica Aline Orozpe-Olvera, Miguel Armando Ramos-Soto, José Alberto Núñez-Gastélum, Bonifacio Alvarado-Tenorio, Laura Alejandra de la Rosa
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
urease
inhibition
disulfiram
Online Access:http://www.mdpi.com/1420-3049/21/12/1628

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