Fractionated irradiation of MCF7 breast cancer cells rewires a gene regulatory circuit towards a treatment‐resistant stemness phenotype

Fractionated irradiation of MCF7 breast cancer cells rewires a gene regulatory circuit towards a treatment‐resistant stemness phenotype

Radiotherapy is the standard of care for breast cancer. However, surviving radioresistant cells can repopulate following treatment and provoke relapse. Better understanding of the molecular mechanisms of radiation resistance may help to improve treatment of radioresistant tumours. To emulate radiati...

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Bibliographic Details
Main Authors:	Auchi Inalegwu, Bart Cuypers, Jürgen Claesen, Ann Janssen, Amelie Coolkens, Sarah Baatout, Kris Laukens, Winnok H. De Vos, Roel Quintens
Format:	Article
Language:	English
Published:	Wiley 2022-10-01
Series:	Molecular Oncology
Subjects:	breast cancer circular RNA radioresistance relapse‐free survival stemness tamoxifen resistance
Online Access:	https://doi.org/10.1002/1878-0261.13226

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