Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center
Background: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis, usually seronegative for rheumatoid factor. While many patients with PsA do well, there is a group of patients who suffer from severe disease, with progression of articular damage and increased morbidity....
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2022-07-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/43648 |
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| author | Ilyas Baig Shraddha More Milind Nadkar Alhad Mulkalwar Hunaid Haider |
| author_facet | Ilyas Baig Shraddha More Milind Nadkar Alhad Mulkalwar Hunaid Haider |
| author_sort | Ilyas Baig |
| collection | DOAJ |
| description | Background: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis, usually seronegative for rheumatoid factor. While many patients with PsA do well, there is a group of patients who suffer from severe disease, with progression of articular damage and increased morbidity.
Aims and Objectives: This study was aimed at assessing the clinical profile of patients suffering from PsA in a tertiary care hospital.
Materials and Methods: A prospective observational study was carried out with due permission of the Institutional Ethics Committee. Demographic and clinical parameters were tabulated and DAPSA and PASI scores were noted. The comparison was done using Chi-square test and paired t-tests. Outcomes were noted and comparisons were made after 3 months of observation.
Results: A total of 43 patients were included in the study. Most of them belonged to the age group of 26–35 years (25.25%), followed by 36–45 years (23.26%). The mean age of the study subjects was 39.09±8.4 years and median age was 30 years, with roughly an equal number of male (55.81%) and female (44.19%) patients. We observed that along with small joint involvement, which is common in PsA, many patients also showed involvements of large joints. Low backache, dactylitis, and enthesitis were observed in few patients.
Conclusion: The study concludes that there was significant difference between mean DAPSA score at <1 year duration but not after 1 year and there is no correlation between the DAPSA score and PASI score. |
| first_indexed | 2024-04-12T10:12:15Z |
| format | Article |
| id | doaj.art-655abe032e5a4639a294c53f700a4a37 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-12T10:12:15Z |
| publishDate | 2022-07-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-655abe032e5a4639a294c53f700a4a372022-12-22T03:37:17ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762022-07-01137119123https://doi.org/10.3126/ajms.v13i7.43648Clinical profile of patients with psoriatic arthritis in a tertiary healthcare centerIlyas Baig 0https://orcid.org/0000-0003-0818-6009Shraddha More 1https://orcid.org/0000-0002-8525-1524Milind Nadkar 2https://orcid.org/0000-0003-1790-6127Alhad Mulkalwar 3https://orcid.org/0000-0001-6236-3841Hunaid Haider 4https://orcid.org/0000-0003-2844-6648Resident, Department of Medicine, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India Assistant Professor, Department of Medicine, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India Professor and Head, Department of Medicine, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India Intern, Department of Medicine, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India Intern, Department of Medicine, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, IndiaBackground: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis, usually seronegative for rheumatoid factor. While many patients with PsA do well, there is a group of patients who suffer from severe disease, with progression of articular damage and increased morbidity. Aims and Objectives: This study was aimed at assessing the clinical profile of patients suffering from PsA in a tertiary care hospital. Materials and Methods: A prospective observational study was carried out with due permission of the Institutional Ethics Committee. Demographic and clinical parameters were tabulated and DAPSA and PASI scores were noted. The comparison was done using Chi-square test and paired t-tests. Outcomes were noted and comparisons were made after 3 months of observation. Results: A total of 43 patients were included in the study. Most of them belonged to the age group of 26–35 years (25.25%), followed by 36–45 years (23.26%). The mean age of the study subjects was 39.09±8.4 years and median age was 30 years, with roughly an equal number of male (55.81%) and female (44.19%) patients. We observed that along with small joint involvement, which is common in PsA, many patients also showed involvements of large joints. Low backache, dactylitis, and enthesitis were observed in few patients. Conclusion: The study concludes that there was significant difference between mean DAPSA score at <1 year duration but not after 1 year and there is no correlation between the DAPSA score and PASI score.https://www.nepjol.info/index.php/AJMS/article/view/43648psoriatic arthritisspondyloarthropathysteroids |
| spellingShingle | Ilyas Baig Shraddha More Milind Nadkar Alhad Mulkalwar Hunaid Haider Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center Asian Journal of Medical Sciences psoriatic arthritis spondyloarthropathy steroids |
| title | Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center |
| title_full | Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center |
| title_fullStr | Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center |
| title_full_unstemmed | Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center |
| title_short | Clinical profile of patients with psoriatic arthritis in a tertiary healthcare center |
| title_sort | clinical profile of patients with psoriatic arthritis in a tertiary healthcare center |
| topic | psoriatic arthritis spondyloarthropathy steroids |
| url | https://www.nepjol.info/index.php/AJMS/article/view/43648 |
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