Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study
Mild cognitive impairment (MCI) is considered to be the limit between the cognitive changes of aging and early dementia; thus, discriminating between participants with and without MCI is important. In the present study, we aimed to examine the differences in the cerebral oxyhemoglobin signal between...
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MDPI AG
2022-11-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/12/12/1636 |
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| author | Shingo Takahashi Yosuke Tomita Shigeya Tanaka Noriko Sakurai Naoki Kodama |
| author_facet | Shingo Takahashi Yosuke Tomita Shigeya Tanaka Noriko Sakurai Naoki Kodama |
| author_sort | Shingo Takahashi |
| collection | DOAJ |
| description | Mild cognitive impairment (MCI) is considered to be the limit between the cognitive changes of aging and early dementia; thus, discriminating between participants with and without MCI is important. In the present study, we aimed to examine the differences in the cerebral oxyhemoglobin signal between individuals with and without MCI. The cerebral oxyhemoglobin signal was measured when the participants (young and elderly controls as well as patients with MCI) performed category fluency, finger tapping, and dual tasks using head-mounted near-infrared spectroscopy; the results were compared between the groups. The cerebral oxyhemoglobin signal trended toward the highest values during the category fluency task in young participants and during the finger-tapping task in elderly participants regardless of the MCI status. The area under the curve was approximately 0.5, indicating a low discrimination ability between elderly participants with and without MCI. The measurement of the blood flow in the prefrontal cortex may not accurately quantify cognitive and motor performance to detect MCI. Finger tapping may increase cerebral blood flow in individuals with and without MCI during the task. |
| first_indexed | 2024-03-09T17:16:11Z |
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| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T17:16:11Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
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| series | Brain Sciences |
| spelling | doaj.art-655c66d3dbc4450fb419208a405fb7352023-11-24T13:39:07ZengMDPI AGBrain Sciences2076-34252022-11-011212163610.3390/brainsci12121636Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy StudyShingo Takahashi0Yosuke Tomita1Shigeya Tanaka2Noriko Sakurai3Naoki Kodama4Department of Healthcare Informatics, Faculty of Health and Welfare, Takasaki University of Health and Welfare, 37-1 Nakaorui-machi, Takasaki 370-0033, JapanDepartment of Physical Therapy, Faculty of Health Care, Takasaki University of Health and Welfare, Takasaki 370-0033, JapanDepartment of Physical Therapy, Faculty of Health Care, Takasaki University of Health and Welfare, Takasaki 370-0033, JapanDepartment of Radiological Technology, Faculty of Medical Technology, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata 950-3198, JapanDepartment of Radiological Technology, Faculty of Medical Technology, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata 950-3198, JapanMild cognitive impairment (MCI) is considered to be the limit between the cognitive changes of aging and early dementia; thus, discriminating between participants with and without MCI is important. In the present study, we aimed to examine the differences in the cerebral oxyhemoglobin signal between individuals with and without MCI. The cerebral oxyhemoglobin signal was measured when the participants (young and elderly controls as well as patients with MCI) performed category fluency, finger tapping, and dual tasks using head-mounted near-infrared spectroscopy; the results were compared between the groups. The cerebral oxyhemoglobin signal trended toward the highest values during the category fluency task in young participants and during the finger-tapping task in elderly participants regardless of the MCI status. The area under the curve was approximately 0.5, indicating a low discrimination ability between elderly participants with and without MCI. The measurement of the blood flow in the prefrontal cortex may not accurately quantify cognitive and motor performance to detect MCI. Finger tapping may increase cerebral blood flow in individuals with and without MCI during the task.https://www.mdpi.com/2076-3425/12/12/1636near-infrared spectroscopymild cognitive impairmentfinger tappingcategory fluency taskdual task |
| spellingShingle | Shingo Takahashi Yosuke Tomita Shigeya Tanaka Noriko Sakurai Naoki Kodama Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study Brain Sciences near-infrared spectroscopy mild cognitive impairment finger tapping category fluency task dual task |
| title | Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study |
| title_full | Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study |
| title_fullStr | Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study |
| title_full_unstemmed | Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study |
| title_short | Prefrontal Cerebral Oxygenated Hemoglobin Concentration during the Category Fluency and Finger-Tapping Tasks in Adults with and without Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study |
| title_sort | prefrontal cerebral oxygenated hemoglobin concentration during the category fluency and finger tapping tasks in adults with and without mild cognitive impairment a near infrared spectroscopy study |
| topic | near-infrared spectroscopy mild cognitive impairment finger tapping category fluency task dual task |
| url | https://www.mdpi.com/2076-3425/12/12/1636 |
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