Macroautophagy regulation during HIV-1 infection of CD4+ T cells and macrophages

Macroautophagy regulation during HIV-1 infection of CD4+ T cells and macrophages

Autophagy is an intracellular mechanism whereby pathogens, particularly viruses, are destroyed in autolysosomes after their entry into targets cells. Therefore, to survive and replicate in host cells, viruses have developed multiple strategies to either counteract or exploit this process. The aim of...

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Bibliographic Details
Main Authors: Sophie eBorel, Lucile eEspert, Martine eBiard-Piechaczyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Immunology
Subjects:
Autophagy
HIV-1
Infection
Macrophages
CD4+ T cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00097/full

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