THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS

The aim of the study was to evaluate foot bone mineral density (BMD) in diabetes mellitus (DM) complicated with distal neuropathy (DN). Materials and methods. 61 patients with DM (DM1-27, DM2-34) were included. 37patients had Charcot osteoarthropathy (the 1st group), the 2nd group (13 patients) with...

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Main Authors: N A Molitvoslovova, T O Zernova, M V Yaroslavtseva, G R Galstyan
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-12-01
Series:Остеопороз и остеопатии
Subjects:
Online Access:https://endojournals.ru/index.php/osteo/article/view/8843
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author N A Molitvoslovova
T O Zernova
M V Yaroslavtseva
G R Galstyan
author_facet N A Molitvoslovova
T O Zernova
M V Yaroslavtseva
G R Galstyan
author_sort N A Molitvoslovova
collection DOAJ
description The aim of the study was to evaluate foot bone mineral density (BMD) in diabetes mellitus (DM) complicated with distal neuropathy (DN). Materials and methods. 61 patients with DM (DM1-27, DM2-34) were included. 37patients had Charcot osteoarthropathy (the 1st group), the 2nd group (13 patients) with severe DN, the 3rd group (11 patients) with mild DN, and control group consisted of 15 healthy people. All patients underwent dual energy X-ray absorptiometry (DXA) Lunar Prodigy scan. BMD was measured in lumbar spine, hip and radius. Foot BMD was measured using the «Total Body» region’s analysis. Results. There was a significant difference in foot BMD between controls and the 1st (р=0,031) and the 3rd (р=0,027) groups with no significant difference between the groups of patients. Foot BMD significantly correlated with spine, hip and radiusBMD (г=0,5-0,63, р<0,00001), BMI (r=0,4, р=0,000). Negative correlation was found between foot BMD and diabetes duration (r=-0,3, p<0,005) and HbA1c (r=-0,2, р=0,045). No correlation was found between DN and foot BMD. Conclusion. No association between severity of DN and foot BMD was found.
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spelling doaj.art-6563a2cc88f9458786ba833c7ff8efba2022-12-21T22:04:38ZengEndocrinology Research CentreОстеопороз и остеопатии2072-26802311-07162013-12-01161141710.14341/osteo2013114-177888THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUSN A Molitvoslovova0T O Zernova1M V Yaroslavtseva2G R Galstyan3ФГБУ «Эндокринологический научный центр» Минздрава РоссииФГБУ «Эндокринологический научный центр» Минздрава РоссииФГБУ «Эндокринологический научный центр» Минздрава РоссииФГБУ «Эндокринологический научный центр» Минздрава РоссииThe aim of the study was to evaluate foot bone mineral density (BMD) in diabetes mellitus (DM) complicated with distal neuropathy (DN). Materials and methods. 61 patients with DM (DM1-27, DM2-34) were included. 37patients had Charcot osteoarthropathy (the 1st group), the 2nd group (13 patients) with severe DN, the 3rd group (11 patients) with mild DN, and control group consisted of 15 healthy people. All patients underwent dual energy X-ray absorptiometry (DXA) Lunar Prodigy scan. BMD was measured in lumbar spine, hip and radius. Foot BMD was measured using the «Total Body» region’s analysis. Results. There was a significant difference in foot BMD between controls and the 1st (р=0,031) and the 3rd (р=0,027) groups with no significant difference between the groups of patients. Foot BMD significantly correlated with spine, hip and radiusBMD (г=0,5-0,63, р<0,00001), BMI (r=0,4, р=0,000). Negative correlation was found between foot BMD and diabetes duration (r=-0,3, p<0,005) and HbA1c (r=-0,2, р=0,045). No correlation was found between DN and foot BMD. Conclusion. No association between severity of DN and foot BMD was found.https://endojournals.ru/index.php/osteo/article/view/8843дистальная диабетическая полинейропатияостеопорозсахарный диабет
spellingShingle N A Molitvoslovova
T O Zernova
M V Yaroslavtseva
G R Galstyan
THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS
Остеопороз и остеопатии
дистальная диабетическая полинейропатия
остеопороз
сахарный диабет
title THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS
title_full THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS
title_fullStr THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS
title_full_unstemmed THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS
title_short THE RELATIONSHIP OF THE DISTAL DIABETIC POLYNEUROPATHY WITH PARAMETERS OF FOOT BONE MINERAL DENSITY IN PATIENTS WITH DIABETES MELLITUS
title_sort relationship of the distal diabetic polyneuropathy with parameters of foot bone mineral density in patients with diabetes mellitus
topic дистальная диабетическая полинейропатия
остеопороз
сахарный диабет
url https://endojournals.ru/index.php/osteo/article/view/8843
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