Interfacial Chemistry and the Design of Solid-Phase Nucleic Acid Hybridization Assays Using Immobilized Quantum Dots as Donors in Fluorescence Resonance Energy Transfer

Interfacial Chemistry and the Design of Solid-Phase Nucleic Acid Hybridization Assays Using Immobilized Quantum Dots as Donors in Fluorescence Resonance Energy Transfer

The use of quantum dots (QDs) as donors in fluorescence resonance energy transfer (FRET) offer several advantages for the development of multiplexed solid-phase QD-FRET nucleic acid hybridization assays. Designs for multiplexing have been demonstrated, but important challenges remain in the optimiza...

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Bibliographic Details
Main Authors: Ulrich J. Krull, W. Russ Algar
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Sensors
Subjects:
active area
biosensor
DNA
fluorescence resonance energy transfer
immobilization
regeneration
signal enhancement
quantum dots
Online Access:http://www.mdpi.com/1424-8220/11/6/6214/

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http://www.mdpi.com/1424-8220/11/6/6214/

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