The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain
Post-stroke pain (PSP) is a common complication after stroke and affects patients' quality of life. Currently, drug therapy and non-invasive brain stimulation are common treatments for PSP. Given the poor efficacy of drug therapy and various side effects, non-invasive brain stimulation, such as...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Molecular Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.1091402/full |
| _version_ | 1797959592506818560 |
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| author | Long-Jin Pan Long-Jin Pan Hui-Qi Zhu Hui-Qi Zhu Xin-An Zhang Xue-Qiang Wang Xue-Qiang Wang |
| author_facet | Long-Jin Pan Long-Jin Pan Hui-Qi Zhu Hui-Qi Zhu Xin-An Zhang Xue-Qiang Wang Xue-Qiang Wang |
| author_sort | Long-Jin Pan |
| collection | DOAJ |
| description | Post-stroke pain (PSP) is a common complication after stroke and affects patients' quality of life. Currently, drug therapy and non-invasive brain stimulation are common treatments for PSP. Given the poor efficacy of drug therapy and various side effects, non-invasive brain stimulation, such as repetitive transcranial magnetic stimulation (rTMS), has been accepted by many patients and attracted the attention of many researchers because of its non-invasive and painless nature. This article reviews the therapeutic effect of rTMS on PSP and discusses the possible mechanisms. In general, rTMS has a good therapeutic effect on PSP. Possible mechanisms of its analgesia include altering cortical excitability and synaptic plasticity, modulating the release of related neurotransmitters, and affecting the structural and functional connectivity of brain regions involved in pain processing and modulation. At present, studies on the mechanism of rTMS in the treatment of PSP are lacking, so we hope this review can provide a theoretical basis for future mechanism studies. |
| first_indexed | 2024-04-11T00:34:53Z |
| format | Article |
| id | doaj.art-6567f373f4d746649942446e61fd2c4e |
| institution | Directory Open Access Journal |
| issn | 1662-5099 |
| language | English |
| last_indexed | 2024-04-11T00:34:53Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Molecular Neuroscience |
| spelling | doaj.art-6567f373f4d746649942446e61fd2c4e2023-01-06T23:40:42ZengFrontiers Media S.A.Frontiers in Molecular Neuroscience1662-50992023-01-011510.3389/fnmol.2022.10914021091402The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke painLong-Jin Pan0Long-Jin Pan1Hui-Qi Zhu2Hui-Qi Zhu3Xin-An Zhang4Xue-Qiang Wang5Xue-Qiang Wang6College of Kinesiology, Shenyang Sport University, Shenyang, ChinaDepartment of Sport Rehabilitation, Shanghai University of Sport, Shanghai, ChinaCollege of Kinesiology, Shenyang Sport University, Shenyang, ChinaDepartment of Sport Rehabilitation, Shanghai University of Sport, Shanghai, ChinaCollege of Kinesiology, Shenyang Sport University, Shenyang, ChinaDepartment of Sport Rehabilitation, Shanghai University of Sport, Shanghai, ChinaDepartment of Rehabilitation Medicine, Shanghai Shangti Orthopaedic Hospital, Shanghai, ChinaPost-stroke pain (PSP) is a common complication after stroke and affects patients' quality of life. Currently, drug therapy and non-invasive brain stimulation are common treatments for PSP. Given the poor efficacy of drug therapy and various side effects, non-invasive brain stimulation, such as repetitive transcranial magnetic stimulation (rTMS), has been accepted by many patients and attracted the attention of many researchers because of its non-invasive and painless nature. This article reviews the therapeutic effect of rTMS on PSP and discusses the possible mechanisms. In general, rTMS has a good therapeutic effect on PSP. Possible mechanisms of its analgesia include altering cortical excitability and synaptic plasticity, modulating the release of related neurotransmitters, and affecting the structural and functional connectivity of brain regions involved in pain processing and modulation. At present, studies on the mechanism of rTMS in the treatment of PSP are lacking, so we hope this review can provide a theoretical basis for future mechanism studies.https://www.frontiersin.org/articles/10.3389/fnmol.2022.1091402/fullrTMSstrokepainmechanismstherapyreview |
| spellingShingle | Long-Jin Pan Long-Jin Pan Hui-Qi Zhu Hui-Qi Zhu Xin-An Zhang Xue-Qiang Wang Xue-Qiang Wang The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain Frontiers in Molecular Neuroscience rTMS stroke pain mechanisms therapy review |
| title | The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain |
| title_full | The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain |
| title_fullStr | The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain |
| title_full_unstemmed | The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain |
| title_short | The mechanism and effect of repetitive transcranial magnetic stimulation for post-stroke pain |
| title_sort | mechanism and effect of repetitive transcranial magnetic stimulation for post stroke pain |
| topic | rTMS stroke pain mechanisms therapy review |
| url | https://www.frontiersin.org/articles/10.3389/fnmol.2022.1091402/full |
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