Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid

Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely...

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Main Authors: Petrović Božana, Krstić Maja, Mudrinić Tihana, Čebela Maria, Dutour-Sikirić Maja
Format: Article
Language:English
Published: Serbian Medical Society - Dental Section, Belgrade 2022-01-01
Series:Stomatološki glasnik Srbije
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0039-1743/2022/0039-17432202082P.pdf
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author Petrović Božana
Krstić Maja
Mudrinić Tihana
Čebela Maria
Dutour-Sikirić Maja
author_facet Petrović Božana
Krstić Maja
Mudrinić Tihana
Čebela Maria
Dutour-Sikirić Maja
author_sort Petrović Božana
collection DOAJ
description Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications.
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spelling doaj.art-656832502b6243e8a9ef3ef321d84ff22022-12-22T02:17:47ZengSerbian Medical Society - Dental Section, BelgradeStomatološki glasnik Srbije0039-17431452-37012022-01-01692828810.2298/SGS2202082P0039-17432202082PMg and Si substituted hydroxyapatite: Behaviour in simulated body fluidPetrović Božana0Krstić Maja1Mudrinić Tihana2https://orcid.org/0000-0001-7467-8330Čebela Maria3https://orcid.org/0000-0001-6120-6924Dutour-Sikirić Maja4University of Belgrade, Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Belgrade, SerbiaUniversity of Belgrade, Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Belgrade, SerbiaUniversity of Belgrade, Institute of Chemistry, Technology and Metallurgy - National Institute of the Republic of Serbia, Belgrade, SerbiaUniversity of Belgrade, Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Belgrade, SerbiaRuđer Bošković Institute, Zagreb, CroatiaDue to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications.https://scindeks-clanci.ceon.rs/data/pdf/0039-1743/2022/0039-17432202082P.pdfsubstituted hydroxyapatitemagnesiumsiliconsbf
spellingShingle Petrović Božana
Krstić Maja
Mudrinić Tihana
Čebela Maria
Dutour-Sikirić Maja
Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
Stomatološki glasnik Srbije
substituted hydroxyapatite
magnesium
silicon
sbf
title Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
title_full Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
title_fullStr Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
title_full_unstemmed Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
title_short Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
title_sort mg and si substituted hydroxyapatite behaviour in simulated body fluid
topic substituted hydroxyapatite
magnesium
silicon
sbf
url https://scindeks-clanci.ceon.rs/data/pdf/0039-1743/2022/0039-17432202082P.pdf
work_keys_str_mv AT petrovicbozana mgandsisubstitutedhydroxyapatitebehaviourinsimulatedbodyfluid
AT krsticmaja mgandsisubstitutedhydroxyapatitebehaviourinsimulatedbodyfluid
AT mudrinictihana mgandsisubstitutedhydroxyapatitebehaviourinsimulatedbodyfluid
AT cebelamaria mgandsisubstitutedhydroxyapatitebehaviourinsimulatedbodyfluid
AT dutoursikiricmaja mgandsisubstitutedhydroxyapatitebehaviourinsimulatedbodyfluid