Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely...
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Format: | Article |
Language: | English |
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Serbian Medical Society - Dental Section, Belgrade
2022-01-01
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Series: | Stomatološki glasnik Srbije |
Subjects: | |
Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/0039-1743/2022/0039-17432202082P.pdf |
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author | Petrović Božana Krstić Maja Mudrinić Tihana Čebela Maria Dutour-Sikirić Maja |
author_facet | Petrović Božana Krstić Maja Mudrinić Tihana Čebela Maria Dutour-Sikirić Maja |
author_sort | Petrović Božana |
collection | DOAJ |
description | Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications. |
first_indexed | 2024-04-14T02:28:53Z |
format | Article |
id | doaj.art-656832502b6243e8a9ef3ef321d84ff2 |
institution | Directory Open Access Journal |
issn | 0039-1743 1452-3701 |
language | English |
last_indexed | 2024-04-14T02:28:53Z |
publishDate | 2022-01-01 |
publisher | Serbian Medical Society - Dental Section, Belgrade |
record_format | Article |
series | Stomatološki glasnik Srbije |
spelling | doaj.art-656832502b6243e8a9ef3ef321d84ff22022-12-22T02:17:47ZengSerbian Medical Society - Dental Section, BelgradeStomatološki glasnik Srbije0039-17431452-37012022-01-01692828810.2298/SGS2202082P0039-17432202082PMg and Si substituted hydroxyapatite: Behaviour in simulated body fluidPetrović Božana0Krstić Maja1Mudrinić Tihana2https://orcid.org/0000-0001-7467-8330Čebela Maria3https://orcid.org/0000-0001-6120-6924Dutour-Sikirić Maja4University of Belgrade, Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Belgrade, SerbiaUniversity of Belgrade, Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Belgrade, SerbiaUniversity of Belgrade, Institute of Chemistry, Technology and Metallurgy - National Institute of the Republic of Serbia, Belgrade, SerbiaUniversity of Belgrade, Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Belgrade, SerbiaRuđer Bošković Institute, Zagreb, CroatiaDue to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications.https://scindeks-clanci.ceon.rs/data/pdf/0039-1743/2022/0039-17432202082P.pdfsubstituted hydroxyapatitemagnesiumsiliconsbf |
spellingShingle | Petrović Božana Krstić Maja Mudrinić Tihana Čebela Maria Dutour-Sikirić Maja Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid Stomatološki glasnik Srbije substituted hydroxyapatite magnesium silicon sbf |
title | Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid |
title_full | Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid |
title_fullStr | Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid |
title_full_unstemmed | Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid |
title_short | Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid |
title_sort | mg and si substituted hydroxyapatite behaviour in simulated body fluid |
topic | substituted hydroxyapatite magnesium silicon sbf |
url | https://scindeks-clanci.ceon.rs/data/pdf/0039-1743/2022/0039-17432202082P.pdf |
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