Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen
Rickettsia felis is an emerging pathogen of the transitional group of Rickettsia species and an important cause of febrile illness in Africa. Since the organism’s original discovery in the early 1990s, much research has been directed towards elucidating transmission mechanisms within the primary hos...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-12-01
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| Series: | Tropical Medicine and Infectious Disease |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2414-6366/2/4/64 |
| _version_ | 1798042191187148800 |
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| author | Kelsey P. Legendre Kevin R. Macaluso |
| author_facet | Kelsey P. Legendre Kevin R. Macaluso |
| author_sort | Kelsey P. Legendre |
| collection | DOAJ |
| description | Rickettsia felis is an emerging pathogen of the transitional group of Rickettsia species and an important cause of febrile illness in Africa. Since the organism’s original discovery in the early 1990s, much research has been directed towards elucidating transmission mechanisms within the primary host and reservoir, the cat flea (Ctenocephalides felis). Several mechanisms for vertical and horizontal transmission within this vector have been thoroughly described, as well as transmission to other arthropod vectors, including other species of fleas. However, while a growing number of human cases of flea-borne spotted fever are being reported throughout the world, a definitive transmission mechanism from arthropod host to vertebrate host resulting in disease has not been found. Several possible mechanisms, including bite of infected arthropods and association with infectious arthropod feces, are currently being investigated. |
| first_indexed | 2024-04-11T22:32:02Z |
| format | Article |
| id | doaj.art-656a3bd0797f4441bcdcee997a41d2fa |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-04-11T22:32:02Z |
| publishDate | 2017-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-656a3bd0797f4441bcdcee997a41d2fa2022-12-22T03:59:20ZengMDPI AGTropical Medicine and Infectious Disease2414-63662017-12-01246410.3390/tropicalmed2040064tropicalmed2040064Rickettsia felis: A Review of Transmission Mechanisms of an Emerging PathogenKelsey P. Legendre0Kevin R. Macaluso1Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USADepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USARickettsia felis is an emerging pathogen of the transitional group of Rickettsia species and an important cause of febrile illness in Africa. Since the organism’s original discovery in the early 1990s, much research has been directed towards elucidating transmission mechanisms within the primary host and reservoir, the cat flea (Ctenocephalides felis). Several mechanisms for vertical and horizontal transmission within this vector have been thoroughly described, as well as transmission to other arthropod vectors, including other species of fleas. However, while a growing number of human cases of flea-borne spotted fever are being reported throughout the world, a definitive transmission mechanism from arthropod host to vertebrate host resulting in disease has not been found. Several possible mechanisms, including bite of infected arthropods and association with infectious arthropod feces, are currently being investigated.https://www.mdpi.com/2414-6366/2/4/64Rickettsia felistransmissionfleas |
| spellingShingle | Kelsey P. Legendre Kevin R. Macaluso Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen Tropical Medicine and Infectious Disease Rickettsia felis transmission fleas |
| title | Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen |
| title_full | Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen |
| title_fullStr | Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen |
| title_full_unstemmed | Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen |
| title_short | Rickettsia felis: A Review of Transmission Mechanisms of an Emerging Pathogen |
| title_sort | rickettsia felis a review of transmission mechanisms of an emerging pathogen |
| topic | Rickettsia felis transmission fleas |
| url | https://www.mdpi.com/2414-6366/2/4/64 |
| work_keys_str_mv | AT kelseyplegendre rickettsiafelisareviewoftransmissionmechanismsofanemergingpathogen AT kevinrmacaluso rickettsiafelisareviewoftransmissionmechanismsofanemergingpathogen |