The Role of Signaling Pathways of Inflammation and Oxidative Stress in Development of Senescence and Aging Phenotypes in Cardiovascular Disease
The ASK1-signalosome→p38 MAPK and SAPK/JNK signaling networks promote senescence (in vitro) and aging (in vivo, animal models and human cohorts) in response to oxidative stress and inflammation. These networks contribute to the promotion of age-associated cardiovascular diseases of oxidati...
Main Author: | John Papaconstantinou |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/11/1383 |
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