Constructing Auxin-Inducible Degron Mutants Using an All-in-One Vector

Conditional degron-based methods are powerful for studying protein function because a degron-fused protein can be rapidly and efficiently depleted by adding a defined ligand. Auxin-inducible degron (AID) is a popular technology by which a degron-fused protein can be degraded by adding an auxin. Howe...

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Bibliographic Details
Main Authors: Aisha Yesbolatova, Yuichiro Saito, Masato T. Kanemaki
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/5/103