Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists

Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists

Atherosclerosis is a chronic inflammatory vascular disease. Toll-like receptors (TLRs) are major initiators of inflammation. TLR2 promotes atherosclerosis in LDL receptor (LDLr)-deficient mice fed a high-fat diet (HFD). TLR2 forms heterodimers with TLR1 or TLR6 to enable inflammatory responses in th...

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Bibliographic Details
Main Authors: Linda K. Curtiss, Audrey S. Black, David J. Bonnet, Peter S. Tobias
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Journal of Lipid Research
Subjects:
inflammation
lipids
macrophages
receptors
agonists
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752043189X

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