Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1

Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1

Acute pancreatitis (AP) is a severe and potentially fatal disease caused predominantly by alcohol excess and gallstones, which lacks a specific therapy. The role of Receptor-Interacting Protein Kinase 1 (RIPK1), a key component of programmed necrosis (Necroptosis), is unclear in AP. We assessed the...

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Bibliographic Details
Main Authors: Yulin Ouyang, Li Wen, Jane A. Armstrong, Michael Chvanov, Diane Latawiec, Wenhao Cai, Mohammad Awais, Rajarshi Mukherjee, Wei Huang, Peter J. Gough, John Bertin, Alexei V. Tepikin, Robert Sutton, David N. Criddle
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
acute pancreatitis
receptor-interacting protein kinase 1
RIPK1
necrostatin-1
necroptosis
cell death
Online Access:https://www.mdpi.com/2073-4409/10/5/1035

Internet

https://www.mdpi.com/2073-4409/10/5/1035

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